{"id":"W2559772841","doi":"10.1182/blood.v118.21.430.430","title":"A Gene Expression Signature in Diagnostic Formalin Fixed Paraffin Embedded Tissue Predicts Overall Survival in Locally Advanced and Advanced Stage Classical Hodgkin Lymphoma – a Correlative Study From the E2496 Intergroup Trial","year":2011,"lang":"en","type":"article","venue":"Blood","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University; BC Cancer Agency","funders":"","keywords":"Oncology; Medicine; ABVD; Internal medicine; Log-rank test; Stage (stratigraphy); Proportional hazards model; Clinical trial; Chemotherapy; Biology; Vincristine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002073703,0.0003979892,0.0004970277,0.0003707895,0.0002206348,0.0006997042,0.000347601,0.0005108884,0.001232932],"category_scores_gemma":[0.001512368,0.0002041346,0.0003350823,0.0004446465,0.0004591032,0.0003613559,0.0002860141,0.0006068806,0.0003171276],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002940216,"about_ca_system_score_gemma":0.0001824443,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001816028,"about_ca_topic_score_gemma":0.0002900861,"domain_scores_codex":[0.9995362,0.0001899829,0.00003301468,0.0001153979,0.00008177799,0.00004375979],"domain_scores_gemma":[0.9992126,0.0002554181,0.0002341335,0.0001103627,0.00006789608,0.0001194868],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.1783909,0.004368977,0.693832,0.0004584892,0.001626606,0.0004572058,0.0002889932,0.003356664,0.07533902,0.0001294159,0.002072493,0.03967914],"study_design_scores_gemma":[0.007464012,0.02192573,0.9497491,0.00003821475,0.001026254,0.0009202057,0.0001678565,0.003031686,0.01236869,0.0003331124,0.002933197,0.0000418936],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985803,0.0003566347,0.0001309068,0.00003317852,0.00000875093,0.00005888494,0.000541613,0.000005873214,0.0002836839],"genre_scores_gemma":[0.9969088,0.00009477001,0.0002334743,0.00007378514,0.00002358457,0.0001221008,0.002285729,0.000004688242,0.0002531745],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002073703,"threshold_uncertainty_score":0.01096696,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0182380658208348,"score_gpt":0.2627550317490062,"score_spread":0.2445169659281713,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}