{"id":"W2560022374","doi":"10.1101/gad.288969.116","title":"SUV4-20 activity in the preimplantation mouse embryo controls timely replication","year":2016,"lang":"en","type":"article","venue":"Genes & Development","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Ludwig-Maximilians-Universität München; Ministère de l'Enseignement Supérieur et de la Recherche; Ministère de l'Education Nationale, de l'Enseignement Superieur et de la Recherche; EMBO; Fondation pour la Recherche Médicale; York University; Schlumberger Foundation","keywords":"Biology; Chromatin; Cell biology; Histone; Chromatin remodeling; Replication timing; Genetics; Somatic cell; DNA methylation; Embryo; Gene expression; DNA","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001407812,0.0005623191,0.0002522103,0.000384758,0.0001817171,0.0003996026,0.0004750578,0.0004846122,0.002029394],"category_scores_gemma":[0.000124721,0.0004312466,0.0003308213,0.000151921,0.0002584188,0.0002126368,0.0002877133,0.0007405829,0.0007612917],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004537941,"about_ca_system_score_gemma":0.0002605511,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006969931,"about_ca_topic_score_gemma":0.000957127,"domain_scores_codex":[0.9998257,0.00001799373,0.00001586898,0.00004641601,0.00004354289,0.00005054841],"domain_scores_gemma":[0.9998772,0.00001576968,0.00004165457,0.00001978889,0.000008716862,0.0000368957],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005327232,0.00000573507,0.000124523,0.00001375869,0.000001893579,0.00003432413,0.000007702337,0.00003441318,0.998803,0.0001193139,0.00001315268,0.0007889525],"study_design_scores_gemma":[0.00001346271,0.0001247732,0.004599795,0.000006918223,0.00000959872,0.0001208308,0.00001409965,0.0004395063,0.9921669,0.00006976917,0.002430052,0.000004347415],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9873766,0.003000483,0.004806678,0.0001004743,0.00005808362,0.00004414207,0.000775885,0.0003911266,0.003446613],"genre_scores_gemma":[0.9835736,0.001330527,0.003807839,0.00005327256,0.00001453277,0.00007246194,0.0009645374,0.0001003155,0.01008292],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002029394,"threshold_uncertainty_score":0.006788969,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01665568121675128,"score_gpt":0.2662189301030065,"score_spread":0.2495632488862553,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}