{"id":"W2560150159","doi":"10.1039/c6pp00166a","title":"meso-Acetoxymethyl BODIPY dyes for photodynamic therapy: improved photostability of singlet oxygen photosensitizers","year":2016,"lang":"en","type":"article","venue":"Photochemical & Photobiological Sciences","topic":"Nanoplatforms for cancer theranostics","field":"Engineering","cited_by":44,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; Consejo Nacional de Investigaciones Científicas y Técnicas; Natural Sciences and Engineering Research Council of Canada; McGill University","keywords":"Singlet oxygen; Photosensitizer; Photodynamic therapy; BODIPY; HeLa; Chemistry; Photochemistry; Substituent; Reactive oxygen species; Rose bengal; Oxygen; Biophysics; Combinatorial chemistry; Fluorescence; Biochemistry; Organic chemistry; In vitro; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001275751,0.000238346,0.000155133,0.00008704328,0.00008804713,0.0001424255,0.0001660288,0.0002968051,0.0009594621],"category_scores_gemma":[0.0001203196,0.0001154876,0.0001116384,0.00009273807,0.0001257177,0.0002453437,0.0001653563,0.0003552504,0.0002103776],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002421432,"about_ca_system_score_gemma":0.0001123632,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000586594,"about_ca_topic_score_gemma":0.0007902289,"domain_scores_codex":[0.9999279,0.000008469115,0.000005605356,0.0000175241,0.00001886201,0.0000217156],"domain_scores_gemma":[0.9999554,0.000009516334,0.00001452009,0.000005512908,0.000007169495,0.000007801868],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003246219,0.000003307586,0.00001962666,0.00001587919,0.000001009723,0.00001310758,0.000005843699,0.00004917986,0.9989206,0.00005705894,0.00001762712,0.0008643559],"study_design_scores_gemma":[0.000004358472,0.00004875728,0.0004057923,0.000001421039,0.000004082872,0.00004749931,0.000003457414,0.0005802638,0.9981731,0.00001272906,0.000716461,0.00000210065],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9878973,0.00190689,0.008164049,0.0001566449,0.00002918815,0.00001729378,0.00009048152,0.0001004312,0.001637721],"genre_scores_gemma":[0.9939745,0.0008166761,0.002965548,0.00005821636,0.00000829192,0.00001567706,0.00007057076,0.00001589038,0.002074618],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009594621,"threshold_uncertainty_score":0.00320971,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02370758744708573,"score_gpt":0.2557571572595008,"score_spread":0.232049569812415,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}