{"id":"W2560151975","doi":"10.1158/1078-0432.ccr-16-1922","title":"Biological and Clinical Relevance of Associated Genomic Alterations in MYD88 L265P and non-L265P–Mutated Diffuse Large B-Cell Lymphoma: Analysis of 361 Cases","year":2016,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":128,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Cancer Research; Institut National Du Cancer; Ligue Contre le Cancer","keywords":"Diffuse large B-cell lymphoma; Mutant; Cancer research; Lymphoma; Mutation; Biology; Gene; Genetics; Computational biology; Immunology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002363331,0.00025311,0.0003114117,0.001230942,0.000382154,0.0003736927,0.0003363943,0.0003031711,0.001110865],"category_scores_gemma":[0.0005694678,0.0002677941,0.000320649,0.0005866225,0.0004524575,0.0001559299,0.0005558263,0.0001831363,0.0002667748],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002866031,"about_ca_system_score_gemma":0.0001555502,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001098278,"about_ca_topic_score_gemma":0.001262376,"domain_scores_codex":[0.999694,0.00003228213,0.00003166679,0.0001228861,0.00006473791,0.00005440728],"domain_scores_gemma":[0.9997225,0.0000506652,0.00008478281,0.00004321911,0.00002645723,0.00007241816],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005637049,0.00005676432,0.9684213,0.00004093332,0.00006792103,0.003531823,0.0002447143,0.0001652362,0.02122975,0.00003474443,0.00008879269,0.00555433],"study_design_scores_gemma":[0.0000159051,0.0001511572,0.983518,0.000006606682,0.00006293733,0.0126777,0.0002893679,0.0003750024,0.002328691,0.00004269451,0.000524348,0.000007654164],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9996045,0.000156029,0.00005894225,0.000004887745,7.440275e-7,0.000004613747,0.00009008223,0.000002465064,0.00007770988],"genre_scores_gemma":[0.999597,0.00006553247,0.0000759054,0.000003668073,0.000002074174,0.000003991666,0.0002020898,0.000001678735,0.00004816892],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001230942,"threshold_uncertainty_score":0.003716171,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1757784896698539,"score_gpt":0.496633574874026,"score_spread":0.3208550852041722,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}