{"id":"W2560172367","doi":"10.1182/blood.v124.21.1667.1667","title":"Cell-of-Origin Subtype Classification of Diffuse Large B-Cell Lymphoma Using the Lymph2Cx Assay Retains Relevance in the Context of BCL2 and MYC Expression Status","year":2014,"lang":"en","type":"article","venue":"Blood","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Spinal Cord Injury BC; BC Cancer Agency","funders":"","keywords":"clone (Java method); Germinal center; Tissue microarray; Diffuse large B-cell lymphoma; Immunohistochemistry; Context (archaeology); Lymphoma; Pathology; Biology; Gene expression profiling; Cancer research; Molecular biology; B cell; Antibody; Medicine; Gene; Gene expression; Immunology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005879769,0.000149921,0.000177146,0.0006819077,0.0001903866,0.0004849285,0.0001379541,0.0002056953,0.001490871],"category_scores_gemma":[0.0004678687,0.0001002328,0.0001069033,0.000346317,0.0001939707,0.0001349817,0.0002566147,0.0002084454,0.0003489552],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002306032,"about_ca_system_score_gemma":0.0001028492,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007729263,"about_ca_topic_score_gemma":0.001630741,"domain_scores_codex":[0.9996175,0.0001070923,0.00004871127,0.00009034287,0.00009130212,0.00004505241],"domain_scores_gemma":[0.9996794,0.0001060382,0.00006152992,0.00005624832,0.00006066866,0.00003618996],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001082285,0.00006773068,0.494437,0.00006768045,0.00006797464,0.0002404959,0.000165671,0.0001896775,0.4898022,0.0002134942,0.0003250809,0.01334075],"study_design_scores_gemma":[0.00003474193,0.0004084819,0.8215682,0.00001694469,0.00009831419,0.002055921,0.0002728126,0.003260101,0.1690132,0.0001952463,0.003065166,0.00001082013],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963428,0.0004011631,0.001732962,0.00001726925,0.000005147625,0.00002839668,0.0002879721,0.00002420092,0.001160055],"genre_scores_gemma":[0.9972729,0.00009178505,0.001407151,0.00002589892,0.000003531557,0.00003107055,0.0007246843,0.000007867464,0.0004351694],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001490871,"threshold_uncertainty_score":0.004987419,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02191676216512201,"score_gpt":0.2659651814485902,"score_spread":0.2440484192834682,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}