{"id":"W2560256933","doi":"10.1093/ofid/ofw194.40","title":"Efficacy, Immunogenicity and Safety of an Investigational Subunit Adjuvanted Herpes Zoster Vaccine in Adults Aged 60 Years and Older: Results From the ZOE-50 and ZOE-70 Efficacy Studies","year":2016,"lang":"en","type":"article","venue":"Open Forum Infectious Diseases","topic":"Herpesvirus Infections and Treatments","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Nova Scotia Health Authority; Izaak Walton Killam Health Centre; Dalhousie University; University of Victoria; Health Sciences North","funders":"","keywords":"Medicine; Immunogenicity; Investigational Drugs; Virology; Clinical trial; Immunology; Internal medicine; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00376273,0.0003236533,0.0006301744,0.0002033287,0.0001367464,0.0003345837,0.0001690982,0.0003792472,0.0007847078],"category_scores_gemma":[0.002182249,0.0001334516,0.0009104272,0.0002414839,0.0002278279,0.0002694982,0.0002105365,0.0003769198,0.0001353442],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001911103,"about_ca_system_score_gemma":0.0003252562,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008155668,"about_ca_topic_score_gemma":0.001688692,"domain_scores_codex":[0.9994363,0.000258162,0.00008318934,0.00005962279,0.0001115537,0.00005125225],"domain_scores_gemma":[0.9982115,0.0005903212,0.0005834085,0.00007922994,0.0002894732,0.0002460251],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.2027652,0.005810103,0.5708082,0.004309629,0.01131311,0.0001929577,0.0009143488,0.0006025903,0.01337075,0.0001412066,0.002473406,0.1872986],"study_design_scores_gemma":[0.01386554,0.08016107,0.89237,0.0003958506,0.00623135,0.0002777679,0.0001963737,0.0001930348,0.001530754,0.00007549222,0.004676604,0.00002611941],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9793762,0.01864824,0.0001002418,0.0001665819,0.00004191143,0.0001299541,0.0005279706,0.000003907522,0.001004991],"genre_scores_gemma":[0.9928374,0.005847827,0.0001643046,0.0002859135,0.00007151451,0.00007543281,0.0005086582,0.000001366962,0.0002075403],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00376273,"threshold_uncertainty_score":0.01989949,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01753628225605504,"score_gpt":0.2938688320897463,"score_spread":0.2763325498336913,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}