{"id":"W2560306568","doi":"10.3390/ijms17122041","title":"The Regulation of Tumor Suppressor p63 by the Ubiquitin-Proteasome System","year":2016,"lang":"en","type":"review","venue":"International Journal of Molecular Sciences","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Alberta Heritage Foundation for Medical Research; Fondation pour la Recherche Médicale; Canadian Institutes of Health Research; Women and Children's Health Research Institute; Children's Health Research Institute","keywords":"Transactivation; Ubiquitin; Proteasome; Ubiquitin ligase; Suppressor; Regulator; Cell biology; Biology; Cell cycle; Apoptosis; Metastasis suppressor; Cancer research; Transcription factor; Genetics; Cancer; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001937145,0.0002463391,0.0007372042,0.0002616409,0.000147408,0.0001239629,0.001598542,0.000113506,0.00003250974],"category_scores_gemma":[0.0004330912,0.0001074382,0.0006897868,0.0002635386,0.0006246982,0.0001178567,0.0001400769,0.0003927028,0.00001926992],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003329724,"about_ca_system_score_gemma":0.0011349,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001102756,"about_ca_topic_score_gemma":9.938053e-7,"domain_scores_codex":[0.9957989,0.0003386385,0.001202505,0.0002432271,0.002187567,0.0002292052],"domain_scores_gemma":[0.9959229,0.0003620003,0.002338453,0.000336282,0.0009432789,0.00009703683],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001829248,0.0001249652,0.00000365164,0.001990286,0.002209833,0.0004588536,0.0001157605,0.00003701589,0.03005083,0.01668954,0.005960322,0.942176],"study_design_scores_gemma":[0.0005931405,0.0003140669,0.00000676615,0.02333292,0.0005691223,0.005851806,0.00009197338,0.00003973446,0.00886929,0.0001965828,0.9599646,0.0001700402],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000384244,0.9936426,0.001072326,0.001210847,0.001720184,0.0005598421,0.00006530648,0.00001020618,0.001334455],"genre_scores_gemma":[0.0198685,0.9787166,0.0003032875,0.0001234848,0.0006000837,0.00003765721,0.00001203468,0.0000452044,0.0002931916],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9540042,"threshold_uncertainty_score":0.4381201,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02386584401086792,"score_gpt":0.3244536394980732,"score_spread":0.3005877954872053,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}