{"id":"W2560326572","doi":"10.1021/acschembio.6b00791","title":"Internal Structure and Preferential Protein Binding of Colloidal Aggregates","year":2016,"lang":"en","type":"article","venue":"ACS Chemical Biology","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; National Institutes of Health; Howard Hughes Medical Institute","keywords":"Colloid; Dispersity; Chemistry; Biophysics; Dynamic light scattering; Small-angle X-ray scattering; Nanotechnology; Nanoparticle; Chemical engineering; Materials science; Scattering; Polymer chemistry; Biology; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004245646,0.00008777753,0.0002182394,0.00004483236,0.00001538783,0.000002763955,0.00008025056,0.0001334195,0.0002987433],"category_scores_gemma":[0.0001481686,0.00004504638,0.00003723248,0.00004506615,0.0003418362,0.00001841402,0.0001379598,0.0001207265,0.000007723977],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001370354,"about_ca_system_score_gemma":0.00002827114,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003514795,"about_ca_topic_score_gemma":0.000001931918,"domain_scores_codex":[0.9993652,0.00002250965,0.0001596921,0.0001768931,0.00008179184,0.000193941],"domain_scores_gemma":[0.9996324,0.00009345222,0.00004752465,0.00008058153,0.00005147595,0.00009460376],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006132812,0.00002182617,0.0375714,0.00005147512,0.00005411541,0.000003285734,0.00001325647,9.403273e-10,0.9449238,0.001164714,0.00008259702,0.01550028],"study_design_scores_gemma":[0.0008502321,0.0002580653,0.001628667,0.000119467,0.00001092407,0.00005479181,0.000004157781,0.000001136553,0.9926647,0.001760488,0.00258906,0.00005829132],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980108,0.000226558,0.000009113793,0.001068845,0.00003276065,0.0001401108,0.0000839279,0.000009939397,0.0004179344],"genre_scores_gemma":[0.9983468,0.00006278013,0.000303327,0.00003768019,0.0001380484,0.000005140278,0.00002507611,0.000005847429,0.001075309],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04774095,"threshold_uncertainty_score":0.327103,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01637486844631611,"score_gpt":0.2938163711953049,"score_spread":0.2774415027489888,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}