{"id":"W2560326572","doi":"10.1021/acschembio.6b00791","title":"Internal Structure and Preferential Protein Binding of Colloidal Aggregates","year":2016,"lang":"en","type":"article","venue":"ACS Chemical Biology","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; National Institutes of Health; Howard Hughes Medical Institute","keywords":"Colloid; Dispersity; Chemistry; Biophysics; Dynamic light scattering; Small-angle X-ray scattering; Nanotechnology; Nanoparticle; Chemical engineering; Materials science; Scattering; Polymer chemistry; Biology; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001503136,0.0001848475,0.00018756,0.0003457555,0.0003007519,0.0005859617,0.0002027479,0.0003206937,0.0007393386],"category_scores_gemma":[0.0002927054,0.0002246007,0.000199504,0.0001706531,0.0003765838,0.0001928054,0.000353535,0.0004704325,0.0003898485],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004581437,"about_ca_system_score_gemma":0.0002033114,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00117525,"about_ca_topic_score_gemma":0.0008832743,"domain_scores_codex":[0.9998028,0.0000159207,0.000007729674,0.00007210172,0.00006034761,0.00004122668],"domain_scores_gemma":[0.9997585,0.0000441267,0.00005305627,0.00002558396,0.0000658483,0.00005275456],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001845456,0.000006446481,0.0003964053,0.00001862027,0.000004591118,0.00002860834,0.00004058359,0.00008329874,0.9985084,0.0001785772,0.00005716603,0.0006588058],"study_design_scores_gemma":[0.00000626663,0.00008258218,0.0147003,0.000009309751,0.00001999726,0.0001741748,0.00005234895,0.002404383,0.9807916,0.0001722814,0.001576066,0.000010519],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9878762,0.0008262452,0.006981108,0.00007065716,0.00001595834,0.00001738726,0.0001585163,0.0001122231,0.003941547],"genre_scores_gemma":[0.9957417,0.0002338573,0.002178854,0.00007135435,0.000007264004,0.00001843564,0.0002778955,0.00005213073,0.001418426],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00117525,"threshold_uncertainty_score":0.003324032,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01637486844631611,"score_gpt":0.2938163711953049,"score_spread":0.2774415027489888,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}