{"id":"W2560597565","doi":"10.1007/978-1-4939-6424-6_1","title":"How Genetics Has Helped Piece Together the MAPK Signaling Pathway","year":2016,"lang":"en","type":"review","venue":"Methods in molecular biology","topic":"Fungal Biology and Applications","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Canadian Institutes of Health Research","keywords":"Multicellular organism; Biology; Signal transduction; MAPK/ERK pathway; Cell signaling; Receptor tyrosine kinase; Mechanism (biology); Cell biology; Neuroscience; Genetics; Computational biology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009612673,0.001092577,0.001021008,0.001832472,0.0002502464,0.001177815,0.0008369153,0.001355242,0.003355025],"category_scores_gemma":[0.001216566,0.0003513356,0.0004600732,0.00122925,0.00124489,0.002250927,0.00107623,0.003285643,0.002249528],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008827876,"about_ca_system_score_gemma":0.001212096,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007802199,"about_ca_topic_score_gemma":0.001918219,"domain_scores_codex":[0.999769,0.00003470259,0.0000295636,0.00004518188,0.00009321892,0.00002831068],"domain_scores_gemma":[0.9995103,0.0002565039,0.00004711312,0.00002063491,0.0001117665,0.00005379841],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006834386,0.00004412549,0.0001291028,0.007929218,0.00006888305,0.0001566801,0.00004414009,0.00032913,0.004893898,0.01191585,0.04482424,0.9295964],"study_design_scores_gemma":[0.00001424426,0.00003048194,0.0002431872,0.00110753,0.00005825705,0.0004175432,0.00002326763,0.00006834695,0.0008397247,0.004530068,0.9926516,0.00001565435],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00009444194,0.9954152,0.0008247214,0.0009443091,0.0008579991,0.000004822037,0.00002267623,0.00002198243,0.001813809],"genre_scores_gemma":[0.0007859647,0.9954971,0.0008781297,0.0008497045,0.0005451142,0.000007985113,0.00004787761,0.000006007263,0.00138209],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003355025,"threshold_uncertainty_score":0.01122367,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.109251573227524,"score_gpt":0.4490375725145688,"score_spread":0.3397859992870448,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}