{"id":"W2560624178","doi":"10.1182/blood.v108.11.3742.3742","title":"Effect of Cytosolic Hereditary Spherocytosis Mutations of Human Erythrocyte Anion Exchanger 1 on Its Interaction with Cytoskeletal Protein 4.2.","year":2006,"lang":"en","type":"article","venue":"Blood","topic":"Erythrocyte Function and Pathophysiology","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Band 3; Ankyrin; Cytoskeleton; Hereditary spherocytosis; Membrane protein; Red blood cell; Mutant protein; Mutant; Biology; Spherocytosis; Cytosol; Vesicle-associated membrane protein 8; Cell biology; Ankyrin repeat; Biochemistry; Molecular biology; Chemistry; Cell; Membrane; Enzyme; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001901437,0.0005534553,0.0002804178,0.0002105415,0.0001799413,0.0002637913,0.0002796295,0.0005291767,0.001530551],"category_scores_gemma":[0.0002497547,0.0001662393,0.0003011959,0.0001857329,0.0003143028,0.0001308236,0.0002316246,0.0004277154,0.0003972299],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004693085,"about_ca_system_score_gemma":0.0001896765,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001763611,"about_ca_topic_score_gemma":0.001175591,"domain_scores_codex":[0.9997646,0.00007875371,0.00003233365,0.00003918608,0.00005309942,0.00003200642],"domain_scores_gemma":[0.9997287,0.0001049799,0.0000695399,0.00001887049,0.00001703484,0.00006073962],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003747951,0.000162682,0.0004854749,0.00004352981,0.00002706903,0.0006967559,0.00003608672,0.0002016458,0.9970784,0.0001475252,0.0001436749,0.0006023672],"study_design_scores_gemma":[0.00008225936,0.0006353092,0.01066908,0.00001759353,0.00004989334,0.001407923,0.00005991479,0.004545552,0.9798315,0.00006133008,0.002624147,0.00001549393],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981617,0.0003763537,0.0003404588,0.00009503002,0.00004399014,0.00001706458,0.0002898624,0.00004135641,0.0006341074],"genre_scores_gemma":[0.9981734,0.0001406228,0.0003821996,0.0000461303,0.00001019333,0.00001205834,0.0003166251,0.00002886687,0.000889923],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001763611,"threshold_uncertainty_score":0.005120218,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01442755017593218,"score_gpt":0.2720583728429189,"score_spread":0.2576308226669867,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}