{"id":"W2560624178","doi":"10.1182/blood.v108.11.3742.3742","title":"Effect of Cytosolic Hereditary Spherocytosis Mutations of Human Erythrocyte Anion Exchanger 1 on Its Interaction with Cytoskeletal Protein 4.2.","year":2006,"lang":"en","type":"article","venue":"Blood","topic":"Erythrocyte Function and Pathophysiology","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Band 3; Ankyrin; Cytoskeleton; Hereditary spherocytosis; Membrane protein; Red blood cell; Mutant protein; Mutant; Biology; Spherocytosis; Cytosol; Vesicle-associated membrane protein 8; Cell biology; Ankyrin repeat; Biochemistry; Molecular biology; Chemistry; Cell; Membrane; Enzyme; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001134036,0.0002066535,0.0004608415,0.0001690181,0.00006890111,0.00000389598,0.00005171879,0.0001278899,0.000246157],"category_scores_gemma":[0.00003271221,0.0001576008,0.0001322523,0.0002555328,0.00009182553,0.0000936001,0.00001824433,0.0001986181,0.0000327609],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003073795,"about_ca_system_score_gemma":0.000036828,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001577384,"about_ca_topic_score_gemma":0.00006592894,"domain_scores_codex":[0.9988118,0.0001397895,0.0003417174,0.0002686065,0.0002513796,0.0001867449],"domain_scores_gemma":[0.9992095,0.00009269531,0.0002490389,0.0002500456,0.0001405586,0.00005813096],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001593142,0.001140583,0.001694888,0.0007147267,0.0001399648,0.00003828725,0.0001011749,0.00004302895,0.9935907,0.0001133856,0.000173294,0.0006568918],"study_design_scores_gemma":[0.005685176,0.01554581,0.01154427,0.0004867296,0.0003444689,0.0001333246,0.00006051625,0.00002570371,0.9658981,0.00002056192,0.0001185335,0.0001367903],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954783,0.00009601683,0.00004942989,0.00005681377,0.00009790617,0.0007613784,0.00002040139,0.00006644728,0.003373333],"genre_scores_gemma":[0.9987312,0.000005697312,0.0001626679,0.00003728761,0.0003743114,0.00009895519,0.0001808471,0.00003350036,0.0003755597],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02769251,"threshold_uncertainty_score":0.6426773,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01442755017593218,"score_gpt":0.2720583728429189,"score_spread":0.2576308226669867,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}