{"id":"W2560628113","doi":"10.15252/emmm.201606674","title":"PD‐L1 blockade enhances response of pancreatic ductal adenocarcinoma to radiotherapy","year":2016,"lang":"en","type":"article","venue":"EMBO Molecular Medicine","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":225,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre","funders":"Medical Research Council; Wellcome; Royal Society; Kidani Memorial Trust; Cancer Research UK; Wellcome Trust","keywords":"Blockade; Pancreatic ductal adenocarcinoma; Cancer research; Radiation therapy; Adenocarcinoma; Medicine; Pancreatic carcinoma; Pancreatic cancer; Internal medicine; Oncology; Receptor; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000853947,0.0001825451,0.0002630173,0.0001283721,0.00006416118,0.0001930237,0.00009736456,0.000163848,0.001144444],"category_scores_gemma":[0.0000793289,0.00007151865,0.0001316367,0.00007778924,0.00009542792,0.0001062679,0.0001080469,0.0006008862,0.0002359969],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001513227,"about_ca_system_score_gemma":0.00009470803,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001404497,"about_ca_topic_score_gemma":0.0002044492,"domain_scores_codex":[0.9999363,0.00001410041,0.000005712903,0.00001236316,0.00001270578,0.00001876321],"domain_scores_gemma":[0.9999468,0.00001229799,0.00001005375,0.000006686944,0.000004072674,0.00002013246],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009069195,0.000420878,0.0005077762,0.00006362078,0.000009526409,0.00003004115,0.00001272937,0.0003048641,0.9920615,0.00005255013,0.0001047907,0.005524735],"study_design_scores_gemma":[0.00008988201,0.005829567,0.00853516,0.000008583511,0.00002728347,0.0001884726,0.00002226744,0.002219427,0.9801582,0.00005095629,0.002865723,0.000004540506],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973648,0.0009620552,0.000496596,0.00004755835,0.00002341653,0.00001312721,0.00009286439,0.0000513507,0.0009482186],"genre_scores_gemma":[0.9980214,0.0004086247,0.0003256073,0.00002734993,0.000007201084,0.00001800154,0.0001178342,0.000005265603,0.001068751],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001144444,"threshold_uncertainty_score":0.003828526,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01059972384263337,"score_gpt":0.2804955575501925,"score_spread":0.2698958337075592,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}