{"id":"W2560706611","doi":"10.1182/blood.v108.11.3547.3547","title":"Lenalidomide Plus High-Dose Dexamethasone Provides Improved Overall Survival Compared to High-Dose Dexamethasone Alone for Relapsed or Refractory Multiple Myeloma (MM): Results of 2 Phase III Studies (MM-009, MM-010) and Subgroup Analysis of Patients with Impaired Renal Function.","year":2006,"lang":"en","type":"article","venue":"Blood","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Lenalidomide; Dexamethasone; Medicine; Placebo; Refractory (planetary science); Multiple myeloma; Internal medicine; Randomization; Phases of clinical research; Gastroenterology; Corticosteroid; Urology; Toxicity; Randomized controlled trial; Pathology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001089417,0.0004898723,0.001368936,0.000295712,0.0001431626,0.0005493687,0.0004145676,0.0004329743,0.0021124],"category_scores_gemma":[0.0007429052,0.0002079301,0.001183463,0.000319594,0.0002841523,0.0003392733,0.0002329776,0.001057026,0.000284722],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003185642,"about_ca_system_score_gemma":0.0004092812,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004141135,"about_ca_topic_score_gemma":0.001484178,"domain_scores_codex":[0.9995157,0.0002935891,0.00004272186,0.00006116724,0.00004036044,0.00004643287],"domain_scores_gemma":[0.9994836,0.0001546053,0.0001357279,0.00004284187,0.00002142142,0.0001618293],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.830656,0.01234865,0.008871218,0.0005336518,0.003835919,0.00007371579,0.00007970928,0.0008833199,0.03843248,0.000081935,0.001065665,0.1031378],"study_design_scores_gemma":[0.3544644,0.538121,0.08054979,0.0001847891,0.005845082,0.0004209702,0.0001303339,0.001854706,0.0140357,0.0003831936,0.003956021,0.00005413348],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930454,0.005001065,0.000211822,0.0002221019,0.0001005123,0.0001676075,0.0004214278,0.00003183002,0.000798268],"genre_scores_gemma":[0.9964234,0.001642604,0.000381634,0.0002439307,0.0001024193,0.00007407882,0.0005870482,0.000008419112,0.0005364572],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0021124,"threshold_uncertainty_score":0.007066667,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03302685785422914,"score_gpt":0.2975950705888775,"score_spread":0.2645682127346484,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}