{"id":"W2560800613","doi":"10.1186/s12864-016-3366-y","title":"Exposure of bovine oocytes and embryos to elevated non-esterified fatty acid concentrations: integration of epigenetic and transcriptomic signatures in resultant blastocysts","year":2016,"lang":"en","type":"article","venue":"BMC Genomics","topic":"Reproductive Biology and Fertility","field":"Medicine","cited_by":96,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Cancer Agency; Université Laval","funders":"Medical Research Council; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada; Universiteit Antwerpen; Natural Sciences and Engineering Research Council of Canada; Fonds Wetenschappelijk Onderzoek; European Cooperation in Science and Technology","keywords":"Biology; Epigenetics; Embryo; Transcriptome; Andrology; Oocyte; DNA microarray; Cell biology; Genetics; Bioinformatics; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001575169,0.0001611006,0.0002661724,0.0001147365,0.0001631564,0.0002505314,0.0001618261,0.0002849466,0.001240427],"category_scores_gemma":[0.0001366393,0.000123097,0.0001850367,0.0001031855,0.0001759938,0.0001145654,0.0001917561,0.0004179109,0.0002933004],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002380103,"about_ca_system_score_gemma":0.0001633854,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001212769,"about_ca_topic_score_gemma":0.00222126,"domain_scores_codex":[0.9998521,0.00001358363,0.00001239222,0.00005334262,0.00004143225,0.00002706882],"domain_scores_gemma":[0.9999048,0.00002331525,0.0000248961,0.0000097383,0.00002037753,0.00001693329],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007691106,0.000007173519,0.0003567587,0.00002107747,0.000002593944,0.00003039176,0.00001958672,0.000009702022,0.9990597,0.000009765731,0.000009703402,0.000396582],"study_design_scores_gemma":[0.00001892237,0.00058867,0.05743394,0.00002130506,0.00003421758,0.0003541847,0.0001382272,0.0003708106,0.9388732,0.00005131742,0.002106679,0.000008434456],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907885,0.002236997,0.003415932,0.00008354214,0.00003310469,0.00007098376,0.001220972,0.00002731221,0.002122642],"genre_scores_gemma":[0.9888326,0.001181165,0.003630168,0.0001431508,0.00001217935,0.0001188778,0.00145079,0.00002210069,0.004608857],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001240427,"threshold_uncertainty_score":0.004149675,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02110430785228041,"score_gpt":0.2592410755929461,"score_spread":0.2381367677406657,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}