{"id":"W2561019146","doi":"10.1212/wnl.86.16_supplement.s7.002","title":"Sustained Benefit with Repeated Treatments of OnabotulinumtoxinA in Post-Stroke Lower Limb Spasticity: 1-Year Open-Label Final Results from a Double-Blind, Placebo-Controlled, Phase 3 Trial (S7.002)","year":2016,"lang":"en","type":"article","venue":"Neurology","topic":"Botulinum Toxin and Related Neurological Disorders","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal General Hospital","funders":"","keywords":"Medicine; Placebo; Open label; Stroke (engine); Double blind; Spasticity; Clinical trial; Physical therapy; Internal medicine; Alternative medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002981519,0.001753932,0.003698738,0.0004871396,0.0006394233,0.001173576,0.001055285,0.00230486,0.004578906],"category_scores_gemma":[0.001478222,0.0005311366,0.002586785,0.0003825974,0.001003284,0.001146192,0.000432589,0.003056838,0.000773313],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008492291,"about_ca_system_score_gemma":0.001200573,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001278086,"about_ca_topic_score_gemma":0.002355891,"domain_scores_codex":[0.9991116,0.000334339,0.00007528552,0.0001530098,0.00009478848,0.0002309104],"domain_scores_gemma":[0.9987135,0.0002492985,0.0003923853,0.0001101839,0.0001483589,0.0003863146],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.91812,0.02502484,0.001008349,0.0009316501,0.001585111,0.00009948983,0.0001082466,0.0003771221,0.01235375,0.00004418276,0.001126672,0.03922058],"study_design_scores_gemma":[0.6449887,0.3459331,0.006125971,0.00006275359,0.0005897264,0.00006628468,0.00002679091,0.0003377877,0.001312733,0.00006938961,0.0004668006,0.00002002786],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.988417,0.004710509,0.0006895442,0.0003427911,0.0002044765,0.003191922,0.001200318,0.0001970157,0.001046421],"genre_scores_gemma":[0.9877419,0.002399194,0.0013423,0.0009473223,0.0003550813,0.003885248,0.001595122,0.00003381564,0.001699955],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004578906,"threshold_uncertainty_score":0.01576793,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04884073944647098,"score_gpt":0.3133805074971279,"score_spread":0.2645397680506569,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}