{"id":"W2561142812","doi":"10.1182/blood.v114.22.170.170","title":"Phase II Dose-Finding Study with TAK-442, An Oral Factor Xa Inhibitor, in Patients Undergoing Elective Knee Arthroplasty.","year":2009,"lang":"en","type":"article","venue":"Blood","topic":"Venous Thromboembolism Diagnosis and Management","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; McGill University Health Centre","funders":"","keywords":"Medicine; Pulmonary embolism; Regimen; Surgery; Deep vein; Venography; Clinical endpoint; Thrombosis; Asymptomatic; Population; Adverse effect; Randomized controlled trial; Anesthesia; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001624608,0.002559983,0.003080416,0.0005449431,0.0004412416,0.001128222,0.0007998076,0.001698245,0.003984703],"category_scores_gemma":[0.001415457,0.001077873,0.001615347,0.0003382362,0.0009199707,0.0009579299,0.0003426647,0.002849572,0.001084662],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005853195,"about_ca_system_score_gemma":0.001593688,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006594518,"about_ca_topic_score_gemma":0.001034231,"domain_scores_codex":[0.9994088,0.0002944533,0.00002864102,0.00009861802,0.00005206179,0.0001174491],"domain_scores_gemma":[0.9992183,0.0001495505,0.0001526603,0.00007805823,0.00006642631,0.000334833],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8826157,0.06739318,0.001345722,0.0005492662,0.0008108343,0.0001104897,0.0001126991,0.0009732689,0.01882537,0.0001637936,0.001765517,0.02533412],"study_design_scores_gemma":[0.7119402,0.2840571,0.001710181,0.00001235868,0.0001694906,0.00005163992,0.00002177758,0.0004570066,0.0008690406,0.00009112445,0.0006033594,0.00001676154],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9881051,0.002547023,0.001019026,0.0005591075,0.0004352065,0.00435088,0.001006235,0.0001637121,0.001813663],"genre_scores_gemma":[0.9801288,0.002374255,0.002701728,0.001743743,0.0006624082,0.007031043,0.00159148,0.00004644553,0.003720117],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003984703,"threshold_uncertainty_score":0.0133301,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01782915316678644,"score_gpt":0.2863147005874999,"score_spread":0.2684855474207135,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}