{"id":"W2561216302","doi":"10.1182/blood.v110.11.1402.1402","title":"Direct and Enhanced Cytotoxicity of the Bcl-2 Family Inhibitor GX15-070 on Rituximab-Sensitive and Rituximab-Resistant B-NHL Clones.","year":2007,"lang":"en","type":"article","venue":"Blood","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Cytostasis; Apoptosis; CHOP; Rituximab; Cancer research; Bcl-2 family; XIAP; Raji cell; Cytotoxicity; Pharmacology; Vincristine; Biology; Caspase; Chemistry; Lymphoma; Immunology; Programmed cell death; Biochemistry; Chemotherapy; Cyclophosphamide","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002592084,0.0003782414,0.0004621545,0.0002815145,0.0001491264,0.0003389006,0.0003886466,0.0003648954,0.00153962],"category_scores_gemma":[0.0001946904,0.0001817096,0.0002970219,0.000222582,0.00017929,0.0001805754,0.0002118896,0.0007209858,0.0007920887],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003064198,"about_ca_system_score_gemma":0.0001933333,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008801059,"about_ca_topic_score_gemma":0.000876699,"domain_scores_codex":[0.9996488,0.000112981,0.00003102998,0.00003595603,0.00009631072,0.00007502118],"domain_scores_gemma":[0.9998226,0.00006249722,0.00002296832,0.00003209025,0.00002682714,0.00003307551],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000391535,0.0003623164,0.0004061803,0.00005684682,0.00001885917,0.00007141996,0.00004920583,0.0001675493,0.9937938,0.0001204852,0.0002230796,0.00433873],"study_design_scores_gemma":[0.0002265754,0.004989913,0.0125343,0.00001436938,0.00006076297,0.0006193424,0.00004015946,0.002673979,0.9761948,0.00004404445,0.002592086,0.000009601096],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995248,0.001393508,0.0005249802,0.0000720205,0.00003293995,0.00005423095,0.0003858104,0.00005436683,0.002233995],"genre_scores_gemma":[0.9948263,0.0007047249,0.001005414,0.00008237918,0.00001680416,0.00005827992,0.001355265,0.00001701444,0.001933822],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00153962,"threshold_uncertainty_score":0.005150557,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004899064023516795,"score_gpt":0.2062292170854741,"score_spread":0.2013301530619573,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}