{"id":"W2561251250","doi":"10.1182/blood.v110.11.1327.1327","title":"The MHC I Immunopeptidome Is Moulded by the Transcriptome and Conceals a Tissue-Specific Signature.","year":2007,"lang":"en","type":"article","venue":"Blood","topic":"vaccines and immunoinformatics approaches","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"","keywords":"Biology; Major histocompatibility complex; CD8; Transcriptome; MHC class I; Epitope; Cell biology; Immunosurveillance; Cytotoxic T cell; Computational biology; Immune system; Antigen; Gene; Immunology; Genetics; Gene expression; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004325455,0.0001561464,0.0001155626,0.00001246132,0.000367623,0.0001310738,0.0003096536,0.0001355265,0.00001169323],"category_scores_gemma":[0.00001387694,0.00008742855,0.00005963852,0.00007736286,0.0001431499,0.000005610512,0.00006752228,0.0001472237,0.000006648691],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003133294,"about_ca_system_score_gemma":0.00001716033,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009197356,"about_ca_topic_score_gemma":0.000004551108,"domain_scores_codex":[0.9991354,0.00002050871,0.0002625533,0.000168294,0.0001202668,0.0002929964],"domain_scores_gemma":[0.9993917,0.00003247244,0.0000782242,0.0004061988,0.00004467254,0.00004672433],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005049789,0.00005171985,0.00006962226,0.000008054055,0.00008407591,6.552169e-7,0.0004609819,2.524921e-7,0.9828048,0.0001695211,0.01106356,0.005236205],"study_design_scores_gemma":[0.001007948,0.0001615263,0.0006995922,0.000004780347,0.00002717296,0.00003805707,0.0006089017,0.000003534514,0.5305744,0.00005171739,0.4666887,0.0001337383],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9380156,0.05840766,0.0004552163,0.0007444129,0.0001026056,0.0003294985,0.00002973501,0.00001137835,0.001903933],"genre_scores_gemma":[0.994742,0.002717587,0.0001016194,0.0005160029,0.0001109646,0.00001531724,0.00004200554,0.00001836099,0.001736085],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4556251,"threshold_uncertainty_score":0.3565233,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008507060383153152,"score_gpt":0.22630654334234,"score_spread":0.2177994829591868,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}