{"id":"W2561251250","doi":"10.1182/blood.v110.11.1327.1327","title":"The MHC I Immunopeptidome Is Moulded by the Transcriptome and Conceals a Tissue-Specific Signature.","year":2007,"lang":"en","type":"article","venue":"Blood","topic":"vaccines and immunoinformatics approaches","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"","keywords":"Biology; Major histocompatibility complex; CD8; Transcriptome; MHC class I; Epitope; Cell biology; Immunosurveillance; Cytotoxic T cell; Computational biology; Immune system; Antigen; Gene; Immunology; Genetics; Gene expression; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001056199,0.0002832737,0.0001757322,0.0002528683,0.000189311,0.0004491202,0.0001296537,0.0002211645,0.0008857956],"category_scores_gemma":[0.0001366978,0.0001280361,0.0001961329,0.0003010489,0.0001888864,0.0002124773,0.0002211864,0.0003857022,0.0004772618],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001811688,"about_ca_system_score_gemma":0.0001957025,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002356107,"about_ca_topic_score_gemma":0.0003482852,"domain_scores_codex":[0.9998901,0.000006955739,0.000005325141,0.00005126104,0.00002339121,0.00002296157],"domain_scores_gemma":[0.9998671,0.00002010235,0.00005116126,0.00001088733,0.00002077638,0.00003003167],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003593256,0.000002552128,0.0008527967,0.00002501564,0.000003444646,0.0000221497,0.000007727057,0.00001929913,0.9980385,0.00003683347,0.00002014485,0.0009356569],"study_design_scores_gemma":[0.000009045475,0.0003150866,0.220988,0.0000382906,0.00009029001,0.001276061,0.0001643379,0.002404715,0.7666748,0.0003246925,0.007700329,0.00001442838],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9836575,0.00223579,0.009802767,0.00008978811,0.00003758219,0.00002065177,0.002330951,0.0001087133,0.001716127],"genre_scores_gemma":[0.9840282,0.001232943,0.006569406,0.0001272718,0.00003653492,0.0000374385,0.004440216,0.000056071,0.003471955],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008857956,"threshold_uncertainty_score":0.002963245,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008507060383153152,"score_gpt":0.22630654334234,"score_spread":0.2177994829591868,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}