{"id":"W2561520378","doi":"10.1158/1557-3125.advbc-a108","title":"Abstract A108: Distinct immune suppressive myeloid cell populations are induced by hypoxic mammary tumors and differentially promote metastatic tumor growth","year":2013,"lang":"en","type":"article","venue":"Molecular Cancer Research","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Myeloid-derived Suppressor Cell; Immune system; Cancer research; Myeloid; Metastasis; Tumor microenvironment; Biology; Primary tumor; Mammary tumor; Immunology; Cancer; Suppressor; Breast cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000435833,0.000384003,0.0005198247,0.0002896095,0.0004954332,0.000170374,0.0007249548,0.0001840131,0.001753727],"category_scores_gemma":[0.0001831246,0.0003512416,0.0001294447,0.0003994789,0.0004520461,0.0003273599,0.0005679564,0.001265742,0.0003240604],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002181508,"about_ca_system_score_gemma":0.0002787503,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004906211,"about_ca_topic_score_gemma":0.00006528993,"domain_scores_codex":[0.9967156,0.0006407089,0.0005409266,0.0007534233,0.0002770507,0.001072309],"domain_scores_gemma":[0.9983358,0.0001499903,0.0002479229,0.0007037996,0.0004597777,0.0001026946],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006630089,0.0001913065,0.0006082136,0.0002091586,0.0001670107,0.0000720445,0.0001846051,0.00000217601,0.9931197,0.0001227939,0.003346532,0.001910112],"study_design_scores_gemma":[0.001553154,0.000163047,0.08145334,0.0001739599,0.00005180964,0.00003143019,0.000166174,0.00001514733,0.9139001,0.001254433,0.0007947593,0.0004426915],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9777517,0.01818608,0.0001836613,0.001141437,0.0003959002,0.001425748,0.0001403341,0.00006907355,0.000706079],"genre_scores_gemma":[0.996516,0.0001777713,0.0001341826,0.0001129701,0.00002289826,0.0009511295,0.0002463441,0.00008520243,0.001753465],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08084513,"threshold_uncertainty_score":0.999894,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03208069056695326,"score_gpt":0.3050015530211767,"score_spread":0.2729208624542234,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}