{"id":"W2561619633","doi":"10.1182/blood.v106.11.5251.5251","title":"Improved Suicide Gene Therapy: Lentiviral Gene Transfer of Equine Herpes Virus Type 4 Thymidine Kinase into Target Cells.","year":2005,"lang":"en","type":"article","venue":"Blood","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Suicide gene; Thymidine kinase; Genetic enhancement; Ganciclovir; Viral vector; Biology; Virology; CD19; Cancer research; Herpes simplex virus; Gene; Human cytomegalovirus; Virus; Cell; Genetics; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004012776,0.000475419,0.0003073015,0.0003476127,0.0001336771,0.0003831632,0.0004462127,0.000631207,0.0008772354],"category_scores_gemma":[0.0002191019,0.000158413,0.0003440469,0.000211391,0.0002746335,0.0004193024,0.0002704059,0.0007527156,0.0003857788],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005476309,"about_ca_system_score_gemma":0.0002763694,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005850226,"about_ca_topic_score_gemma":0.0005297662,"domain_scores_codex":[0.9997619,0.00004451656,0.00002681917,0.0000570764,0.00006701349,0.00004267607],"domain_scores_gemma":[0.9999075,0.00002030211,0.00003303488,0.00001105398,0.00001730472,0.00001084751],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005927692,0.00007380038,0.0002322171,0.00008442305,0.000009873694,0.00008312236,0.00002528917,0.0003197532,0.9933258,0.0005917911,0.000087951,0.005106675],"study_design_scores_gemma":[0.00002132957,0.0002350337,0.0005764779,0.000006191444,0.00001993639,0.0002617802,0.000005446232,0.00136617,0.9928274,0.00007404131,0.004600586,0.000005699002],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.891657,0.005559667,0.09628411,0.000299457,0.0001838577,0.000483073,0.0008505231,0.0004356907,0.004246522],"genre_scores_gemma":[0.9345441,0.001988129,0.05415869,0.0001109799,0.00002801485,0.0001848353,0.001240112,0.000066458,0.007678684],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008772354,"threshold_uncertainty_score":0.003973365,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01566545720940285,"score_gpt":0.2729608108389068,"score_spread":0.257295353629504,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}