{"id":"W2561697079","doi":"10.1038/cdd.2016.149","title":"S-2HG is an immunometabolite that shapes the T-cell response","year":2016,"lang":"en","type":"letter","venue":"Cell Death and Differentiation","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Computational biology; Cell biology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0002802252,0.0004295622,0.0003651539,0.000231247,0.0004771999,0.0001526797,0.0002915614,0.0009782531,0.0039813],"category_scores_gemma":[0.00002179252,0.0002633833,0.000197571,0.00006288337,0.0001091868,0.0002885507,0.00008869282,0.001061055,0.001225973],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005425837,"about_ca_system_score_gemma":0.00004748163,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004936343,"about_ca_topic_score_gemma":0.000001509812,"domain_scores_codex":[0.9977549,0.0007860839,0.0003599172,0.000547416,0.00008514027,0.0004665508],"domain_scores_gemma":[0.9987332,0.0002622977,0.000370729,0.0005126162,0.00009654792,0.00002458796],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0008504725,0.0000721281,0.0004291749,0.00006415405,0.0001103495,0.000003766388,0.0006703337,6.738792e-8,0.2859297,0.00001944924,0.7086363,0.003214048],"study_design_scores_gemma":[0.001086598,0.0001763304,0.01340113,0.00003619021,0.0001875073,0.00002100205,0.0001048359,0.000008561841,0.0649057,0.00009245966,0.919636,0.0003437101],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7191151,0.03414123,0.00164526,0.2120834,0.01873725,0.001597404,0.0002865427,0.0004086757,0.01198512],"genre_scores_gemma":[0.5283102,0.002176077,0.000007541439,0.1852399,0.0008743737,0.00007539926,0.002264447,0.00008227279,0.2809698],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2689847,"threshold_uncertainty_score":0.9999818,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0188652999129621,"score_gpt":0.2203359106015239,"score_spread":0.2014706106885618,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}