{"id":"W2561755471","doi":"10.1016/j.fct.2016.12.026","title":"UPEI-400, a conjugate of lipoic acid and scopoletin, mediates neuroprotection in a rat model of ischemia/reperfusion","year":2016,"lang":"en","type":"article","venue":"Food and Chemical Toxicology","topic":"Biochemical Acid Research Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph; University of Prince Edward Island","funders":"University of Prince Edward Island; Atlantic Canada Opportunities Agency","keywords":"Scopoletin; Neuroprotection; Pharmacology; Chemistry; Antioxidant; Lipoic acid; Coumarin; Ischemia; Stroke (engine); Biochemistry; Medicine; Internal medicine; Pathology; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003205723,0.0007814369,0.0005648098,0.0007471945,0.0002591259,0.000292941,0.0004530631,0.000658027,0.001778268],"category_scores_gemma":[0.000211893,0.0002614714,0.0003729543,0.0004323878,0.0005821269,0.0007281337,0.0002330685,0.001172051,0.0004105473],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003079556,"about_ca_system_score_gemma":0.0006831263,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007128596,"about_ca_topic_score_gemma":0.000741253,"domain_scores_codex":[0.9998713,0.00002299118,0.00001173043,0.00001800304,0.00002483266,0.00005131202],"domain_scores_gemma":[0.9998203,0.00002340605,0.0000390987,0.00002269765,0.00001948028,0.00007513501],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002384159,0.0002824048,0.0001022917,0.00009589041,0.00002004262,0.0001782122,0.00003265526,0.0000808254,0.992262,0.0002820446,0.00009341068,0.004185973],"study_design_scores_gemma":[0.00007428276,0.00171055,0.0007256836,0.000007255414,0.00004066091,0.0001572091,0.00001716548,0.0003390377,0.9964327,0.00008353005,0.0004074004,0.000004513857],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9906781,0.001787212,0.004619353,0.0001519886,0.00005759031,0.00006571478,0.0001476019,0.0002402287,0.002252217],"genre_scores_gemma":[0.9911702,0.001850966,0.003199295,0.00005427859,0.00003532259,0.00005599678,0.0004117299,0.00002703583,0.003195325],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001778268,"threshold_uncertainty_score":0.005948901,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01204170460729095,"score_gpt":0.2410836099963003,"score_spread":0.2290419053890093,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}