{"id":"W2561816477","doi":"10.1016/j.jes.2016.12.005","title":"Elevated 5-hydroxymethycytosine and cell apoptosis induced by tetrachloro-1,4-benzoquinone in mouse embryonic stem cells","year":2016,"lang":"en","type":"article","venue":"Journal of Environmental Sciences","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Medical Research Council; Natural Sciences and Engineering Research Council of Canada","keywords":"Viability assay; Apoptosis; Annexin; Chemistry; Cell biology; Phosphorylation; Neuroprotection; Molecular biology; Pharmacology; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002213402,0.0002708541,0.0003058801,0.0004380101,0.0002108133,0.0003248425,0.0002932215,0.0004233354,0.001464031],"category_scores_gemma":[0.0001281226,0.0002988486,0.0003434206,0.0002337497,0.0003036683,0.0003004524,0.0002568088,0.0008170159,0.0002683871],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003718458,"about_ca_system_score_gemma":0.0003639584,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001699072,"about_ca_topic_score_gemma":0.002512895,"domain_scores_codex":[0.9997792,0.00003361678,0.00002469595,0.0000462195,0.00005810574,0.00005816773],"domain_scores_gemma":[0.9997535,0.00003548074,0.00007507276,0.00003352576,0.00004004083,0.00006232654],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001171176,0.00001229398,0.0002415037,0.00001250022,0.000004272669,0.00005116733,0.00002980792,0.00001925131,0.9991305,0.00008348269,0.00001325598,0.0002849071],"study_design_scores_gemma":[0.00001273452,0.0002069945,0.006843953,0.000003659772,0.00001857745,0.0001118034,0.00005455918,0.0002764011,0.9916282,0.00007060623,0.0007683203,0.000004216744],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949444,0.001617878,0.002052416,0.0001326655,0.00003690697,0.00001608194,0.0003554822,0.00008848761,0.000755646],"genre_scores_gemma":[0.9965494,0.0004320267,0.0006543821,0.00003469815,0.000007689356,0.00001909013,0.0003473835,0.00001278954,0.001942462],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001699072,"threshold_uncertainty_score":0.004897714,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009367489797615734,"score_gpt":0.2193208924191785,"score_spread":0.2099534026215628,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}