{"id":"W2561985459","doi":"10.1182/blood.v112.11.241.241","title":"Anti-CD3 Therapy Expands the CD4+CD25+ Compartment in Hemophilia a Mice Inducing Tregs That Potently Prevent Factor VIII Inhibitor Formation","year":2008,"lang":"en","type":"article","venue":"Blood","topic":"Hemophilia Treatment and Research","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"CD3; CD8; Medicine; Immunology; IL-2 receptor; Internal medicine; Antigen; Endocrinology; Pharmacology; T cell; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001871421,0.0004563094,0.0004322154,0.0003530133,0.0001572648,0.0002979019,0.0001842118,0.0003196351,0.002133478],"category_scores_gemma":[0.00009955282,0.000175019,0.0002930726,0.0000976827,0.0002742927,0.0001750537,0.0001361607,0.001407645,0.0005211527],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001737286,"about_ca_system_score_gemma":0.0001699048,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004393602,"about_ca_topic_score_gemma":0.0008211307,"domain_scores_codex":[0.9998055,0.00003146108,0.00001369142,0.00003497264,0.00004168969,0.00007266527],"domain_scores_gemma":[0.9998057,0.000022275,0.00003767957,0.00001602306,0.00001492711,0.0001034119],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004907772,0.0002096559,0.0001192319,0.00003261958,0.000004773322,0.00004007837,0.00001325934,0.00007944672,0.9973999,0.00005286219,0.00008541958,0.001471915],"study_design_scores_gemma":[0.0004562958,0.006869955,0.01125043,0.00003572302,0.00005307502,0.0003519332,0.00006789092,0.002355196,0.9751748,0.0001330296,0.00323536,0.00001622005],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960561,0.0007871523,0.0008458134,0.00009052324,0.00005219365,0.00005271656,0.0003854524,0.0001352885,0.001594667],"genre_scores_gemma":[0.9949549,0.0003647882,0.00105002,0.00009679965,0.0000301962,0.00006374629,0.0002580379,0.00003522618,0.003146324],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002133478,"threshold_uncertainty_score":0.007137239,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0657640995945231,"score_gpt":0.2998720441736606,"score_spread":0.2341079445791375,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}