{"id":"W2562489671","doi":"","title":"Characterizing the Molecular Mechanisms Involved in the Formation of Multidrug-tolerant Persister Cells in Streptococcus mutans","year":2015,"lang":"en","type":"dissertation","venue":"TSpace (University of Toronto)","topic":"Streptococcal Infections and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Multidrug tolerance; Streptococcus mutans; Microbiology; Multiple drug resistance; Biology; Computational biology; Chemistry; Biofilm; Genetics; Drug resistance; Bacteria","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001430914,0.0001578463,0.0001176223,0.0001890035,0.0001328605,0.0001958898,0.0001129302,0.0002136424,0.0003223443],"category_scores_gemma":[0.0001566789,0.00007387491,0.0001520265,0.000100363,0.0001698028,0.0002619507,0.0001313736,0.0003122661,0.00008926392],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002152345,"about_ca_system_score_gemma":0.0001515142,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004778199,"about_ca_topic_score_gemma":0.0004402505,"domain_scores_codex":[0.9999421,0.000009163044,0.000005805048,0.00000982932,0.00001630325,0.00001674042],"domain_scores_gemma":[0.999889,0.00003059585,0.00003793189,0.00001155724,0.00001349825,0.0000174787],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004707216,0.0000225134,0.001560682,0.0000175245,0.000002391102,0.00004551638,0.00002703601,0.00004970322,0.9972574,0.00008667378,0.000005564328,0.0008779459],"study_design_scores_gemma":[0.00001746649,0.0007035694,0.1339337,0.000009735299,0.00003160593,0.0005509658,0.0001671917,0.003889972,0.8592262,0.0003693514,0.001089724,0.00001052004],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988924,0.0002982536,0.0006060526,0.00002808834,0.000001484969,0.000007305553,0.00004362626,0.000007620264,0.0001152707],"genre_scores_gemma":[0.9985051,0.000231135,0.0006152141,0.0000118226,0.000003501725,0.00001348973,0.0001290194,0.00000180403,0.0004890268],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004778199,"threshold_uncertainty_score":0.001561642,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02114353794141673,"score_gpt":0.2699885737416067,"score_spread":0.24884503580019,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}