{"id":"W256251970","doi":"10.1016/j.virol.2015.04.019","title":"RNA-binding residues in the N-terminus of APOBEC3G influence its DNA sequence specificity and retrovirus restriction efficiency","year":2015,"lang":"en","type":"article","venue":"Virology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":19,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research; National Institutes of Health","keywords":"APOBEC3G; Deamination; Biology; DNA; Cytidine deaminase; Cytosine; RNA; Biochemistry; Molecular biology; Retrovirus; Enzyme; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006164809,0.0001071027,0.000199943,0.000169697,0.00009306789,0.000007963483,0.0002246655,0.0001685715,0.00002400243],"category_scores_gemma":[0.0003901109,0.00007405755,0.00002323311,0.000231342,0.0003856081,0.00008366274,0.00007712743,0.0002728873,0.0002279592],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005463686,"about_ca_system_score_gemma":0.00008093515,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004800245,"about_ca_topic_score_gemma":0.000173249,"domain_scores_codex":[0.9986235,0.0005147231,0.0002304464,0.000245581,0.0000601002,0.0003256006],"domain_scores_gemma":[0.9993327,0.0002688328,0.00008976959,0.0002283883,0.00005241613,0.00002784128],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0004801912,0.0002050217,0.04732439,0.00001615815,0.00003371669,0.0003014912,0.001627973,0.00002594805,0.9460323,0.001376423,0.0005474748,0.002028872],"study_design_scores_gemma":[0.003799412,0.003514156,0.7805041,0.00004370294,0.00004219036,0.000898108,0.0009778069,0.00001830023,0.2034259,0.001095501,0.005405027,0.0002757928],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965335,0.00153681,0.000008837736,0.0002963789,0.0001011888,0.0002227919,0.00003846391,0.00001543301,0.001246575],"genre_scores_gemma":[0.9994491,0.0002774619,0.00001757158,0.00004929565,0.00001249771,0.00001938805,0.00002120635,0.000004606833,0.0001488858],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7426065,"threshold_uncertainty_score":0.3019979,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05185081242986324,"score_gpt":0.2980815706820977,"score_spread":0.2462307582522344,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}