{"id":"W2562590154","doi":"10.1212/wnl.86.16_supplement.p1.054","title":"A Relative Bioavailability Study of Three Dose Strengths and Four Dose Levels of SD-809, a Potential Treatment for Movement Disorders (P1.054)","year":2016,"lang":"en","type":"article","venue":"Neurology","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Celerion (Canada)","funders":"","keywords":"Bioavailability; Movement disorders; Medicine; Internal medicine; Pharmacology; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001181144,0.0006562918,0.0009557687,0.0003472316,0.0003380547,0.0004528629,0.000398892,0.0006333375,0.002868247],"category_scores_gemma":[0.001332919,0.0004637256,0.0007475367,0.0002709352,0.000587084,0.000523358,0.0002582045,0.001072049,0.000442954],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003782039,"about_ca_system_score_gemma":0.000461866,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008518326,"about_ca_topic_score_gemma":0.0006770848,"domain_scores_codex":[0.9994538,0.0001825452,0.0000370036,0.00016189,0.0001127038,0.0000519913],"domain_scores_gemma":[0.9990692,0.0003070773,0.0002315423,0.0001258634,0.0001035474,0.0001629347],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.3197976,0.02875396,0.006437265,0.0003814262,0.0007555607,0.0001637273,0.0003915538,0.001555021,0.5794241,0.0002100568,0.0006382143,0.06149145],"study_design_scores_gemma":[0.01425636,0.7655144,0.03199914,0.00001947741,0.00120357,0.0004673846,0.0001546653,0.004395289,0.1790079,0.0001845115,0.002725555,0.00007169299],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976221,0.0003052173,0.00120039,0.00004515831,0.00003354389,0.0002616701,0.000222575,0.00002824116,0.000281123],"genre_scores_gemma":[0.9952946,0.0003250319,0.001913802,0.00006235549,0.00005247055,0.0002589977,0.0003205456,0.00001976285,0.001752423],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002868247,"threshold_uncertainty_score":0.009595215,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04536833547596916,"score_gpt":0.2960873137940027,"score_spread":0.2507189783180336,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}