{"id":"W2562624124","doi":"10.1038/cddis.2016.430","title":"Phosphorylated STAT5 regulates p53 expression via BRCA1/BARD1-NPM1 and MDM2","year":2016,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Princess Margaret Cancer Centre; University Health Network","funders":"Vlaamse regering; Veterinärmedizinische Universität Wien; China Scholarship Council; University of Toronto; Fonds Wetenschappelijk Onderzoek; Case Western Reserve University; Cincinnati Children's Hospital Medical Center","keywords":"STAT5; Cancer research; Phosphorylation; NPM1; Nucleophosmin; Biology; Signal transduction; Downregulation and upregulation; Cell biology; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006426037,0.0002033909,0.0002169116,0.0000702826,0.00009257886,0.00002263251,0.00004521054,0.0001008245,0.0002314428],"category_scores_gemma":[0.00009036863,0.0001375645,0.00006830431,0.0000753188,0.0001021282,0.00008184789,0.00006995886,0.00009010558,0.00004104057],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004401521,"about_ca_system_score_gemma":0.0001364961,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002520683,"about_ca_topic_score_gemma":0.000001238696,"domain_scores_codex":[0.9988713,0.00002582013,0.0001819528,0.0004294751,0.0001927982,0.0002986077],"domain_scores_gemma":[0.9982846,0.00004123844,0.00005746649,0.0003599463,0.0000588229,0.001197881],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001530545,0.0002550973,0.01435855,0.0002562348,0.0000388203,0.0005471598,0.0001732025,0.000002996137,0.9550667,0.00006496641,0.0064252,0.02128058],"study_design_scores_gemma":[0.01999294,0.000775159,0.1574411,0.001646742,0.001006183,0.0001027943,0.0001102509,0.000948714,0.7746414,0.003923874,0.03829828,0.001112583],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9820567,0.01491363,0.00057718,0.0004077722,0.0001161483,0.0003696589,0.00005722956,0.0001087202,0.001392937],"genre_scores_gemma":[0.9956941,0.00131648,0.0002478854,0.0003414004,0.0000669799,0.00001977219,0.00003968895,0.00003768942,0.002235985],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1804253,"threshold_uncertainty_score":0.5609716,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006670559581811605,"score_gpt":0.2131861053391705,"score_spread":0.2065155457573589,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}