{"id":"W2563025994","doi":"10.3390/pathogens5040067","title":"Varicella-Zoster Virus Infectious Cycle: ER Stress, Autophagic Flux, and Amphisome-Mediated Trafficking","year":2016,"lang":"en","type":"review","venue":"Pathogens","topic":"Herpesvirus Infections and Treatments","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Public Health Agency of Canada","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health","keywords":"Autophagy; Endoplasmic reticulum; Unfolded protein response; Biology; Cell biology; XBP1; Endoplasmic-reticulum-associated protein degradation; Virology; Virus; ATG5; Endosome; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0001871631,0.0007065267,0.00176585,0.000443721,0.0002083525,0.00006513527,0.00009276646,0.0006128263,0.0009687619],"category_scores_gemma":[0.0001027459,0.0004712208,0.000485641,0.0004130587,0.0001141356,0.00007828021,0.00009736031,0.0004507907,0.001446484],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003160527,"about_ca_system_score_gemma":0.0002708719,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000350692,"about_ca_topic_score_gemma":0.00002630781,"domain_scores_codex":[0.997536,0.0001863357,0.0006827759,0.0007532315,0.0002762325,0.0005654407],"domain_scores_gemma":[0.9983211,0.000302749,0.0003200715,0.0006142366,0.00008582101,0.0003559923],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000006034852,0.0003485187,0.0002463912,0.002996131,0.0007412954,0.0004950256,0.00005580605,1.635898e-7,0.00001304527,0.00001946446,0.0001637095,0.9949144],"study_design_scores_gemma":[0.001089547,0.0001565117,0.0001838052,0.006749647,0.002469146,0.0006732423,0.000003989189,0.000008976552,0.000007146876,0.00001403729,0.9881964,0.0004475229],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001263278,0.9874966,0.00004102597,0.00001539543,0.0006312505,0.001241438,0.0008391619,0.0003239004,0.008147917],"genre_scores_gemma":[0.002491242,0.9942089,0.00007607715,0.0001033839,0.0004630366,0.000214596,0.0004887631,0.0001604711,0.001793507],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9944669,"threshold_uncertainty_score":0.9999445,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02267667686849601,"score_gpt":0.3038197238268096,"score_spread":0.2811430469583136,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}