{"id":"W2563025994","doi":"10.3390/pathogens5040067","title":"Varicella-Zoster Virus Infectious Cycle: ER Stress, Autophagic Flux, and Amphisome-Mediated Trafficking","year":2016,"lang":"en","type":"review","venue":"Pathogens","topic":"Herpesvirus Infections and Treatments","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Public Health Agency of Canada","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health","keywords":"Autophagy; Endoplasmic reticulum; Unfolded protein response; Biology; Cell biology; XBP1; Endoplasmic-reticulum-associated protein degradation; Virology; Virus; ATG5; Endosome; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001828374,0.000635826,0.0007126674,0.0009584817,0.0002066395,0.0006974719,0.000312181,0.0004260663,0.0007953187],"category_scores_gemma":[0.0001301374,0.0001957163,0.000326797,0.0009345462,0.0002446155,0.0006862261,0.0002784339,0.0004368478,0.0004563887],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006784746,"about_ca_system_score_gemma":0.0004955811,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006936857,"about_ca_topic_score_gemma":0.0008536832,"domain_scores_codex":[0.9998868,0.00001553654,0.00001965633,0.00002971186,0.00003043723,0.00001795161],"domain_scores_gemma":[0.9999394,0.0000108296,0.00001915036,0.000002889545,0.00002064656,0.000007019417],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005924843,0.00008127225,0.002450532,0.03379253,0.000323875,0.001207637,0.0003777525,0.001025832,0.3153636,0.00833583,0.008829962,0.6276187],"study_design_scores_gemma":[0.00003442992,0.0006390627,0.02134468,0.002537741,0.0004639029,0.005042296,0.0003058711,0.0006102237,0.114682,0.003751334,0.8505234,0.00006515865],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.008206511,0.9887447,0.0009324047,0.0001444594,0.0001651413,0.00001313577,0.000101004,0.00003214487,0.00166055],"genre_scores_gemma":[0.03073207,0.9656765,0.0007997344,0.0001608413,0.0002033786,0.0000260553,0.0003008861,0.000007905322,0.002092631],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.0009584817,"threshold_uncertainty_score":0.004922748,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02267667686849601,"score_gpt":0.3038197238268096,"score_spread":0.2811430469583136,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}