{"id":"W2563064231","doi":"10.1016/s1525-0016(16)33910-7","title":"301. Efficient Delivery of Nuclear and Cytoplasmic Proteins Fused to HIV-1 Gag Polypeptide By Means of Virus-Like Particles","year":2015,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Université Laval; National Research Council Canada; Stem Cell Network; PROTEO","funders":"","keywords":"Green fluorescent protein; Cytoplasm; Nuclear localization sequence; Fusion protein; Transfection; Biology; Cell biology; Molecular biology; HEK 293 cells; Transactivation; Cell culture; Nuclear transport; Cell nucleus; Gene expression; Gene; Recombinant DNA; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001408802,0.0001558544,0.0001954512,0.00004935498,0.00002504807,0.00001216117,0.0001904991,0.00009242266,0.00001220022],"category_scores_gemma":[0.00001850984,0.0001440783,0.00008169771,0.00008695427,0.00009368257,0.000003305333,0.00008105186,0.00004880539,0.00001554139],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009418433,"about_ca_system_score_gemma":0.00004856619,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000100779,"about_ca_topic_score_gemma":0.00001294455,"domain_scores_codex":[0.9990281,0.0000740707,0.0002333136,0.0002822208,0.0001810932,0.0002012367],"domain_scores_gemma":[0.9992961,0.000005035475,0.00008681686,0.0003420153,0.0001338644,0.0001361253],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006039675,0.0001469128,0.0003188153,0.000007636419,0.00006748159,0.000003738029,0.0003463081,0.0003928712,0.9941388,0.00002099203,0.002062142,0.001890367],"study_design_scores_gemma":[0.0009510823,0.001279296,0.0002269628,0.00002022756,0.00001146748,0.000004624261,0.0002021875,0.000235001,0.987801,0.00001925892,0.009086072,0.0001628666],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960223,0.001939428,0.001372619,0.0001413316,0.00003990564,0.0002841231,0.00005989835,0.000009003026,0.000131433],"genre_scores_gemma":[0.9981854,0.0002098651,0.0007760923,0.0006580752,0.00001760088,0.00001439773,0.00002505512,0.00002768492,0.000085844],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00702393,"threshold_uncertainty_score":0.5875344,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01167313087742943,"score_gpt":0.2251099587549913,"score_spread":0.2134368278775619,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}