{"id":"W2563325642","doi":"10.1093/ofid/ofw172.973","title":"A Phase I Randomized, Observer-Blind, Controlled, Dose Escalation Trial of the Safety and Tolerability of Two Intramuscular Doses of DPX-RSV(A), a Respiratory Syncytial Virus (RSV) Vaccine Containing RSV SH Antigen and a Novel Adjuvant DepoVax, or SH Antigen Co-administered With Aluminum Hydroxide, or Placebo to Healthy Adults ≥50–64 Years of Age","year":2016,"lang":"en","type":"article","venue":"Open Forum Infectious Diseases","topic":"Respiratory viral infections research","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Immunovaccine (Canada); Nova Scotia Health Authority; Izaak Walton Killam Health Centre; Dalhousie University","funders":"","keywords":"Medicine; Tolerability; Palivizumab; Virology; Adverse effect; Randomized controlled trial; Virus; Respiratory system; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002704227,0.003487596,0.003923709,0.0006818706,0.0008685229,0.001347912,0.00191583,0.003291681,0.008409692],"category_scores_gemma":[0.00327408,0.001724834,0.001331635,0.0004984867,0.002889585,0.001973112,0.0007338792,0.004784552,0.001925187],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001256285,"about_ca_system_score_gemma":0.002338997,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008514147,"about_ca_topic_score_gemma":0.001960777,"domain_scores_codex":[0.9985029,0.0005829708,0.00007956446,0.0004437897,0.0001269253,0.0002639784],"domain_scores_gemma":[0.9973672,0.0005556027,0.0006506932,0.0003143409,0.000268208,0.0008439126],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9612508,0.02977174,0.0001665041,0.0002112696,0.000153676,0.00001577281,0.00005377332,0.0001494908,0.003571636,0.0000825468,0.0004742122,0.004098464],"study_design_scores_gemma":[0.8450336,0.1528465,0.000635855,0.00001373517,0.00009045642,0.00001221138,0.00001404041,0.0002285765,0.0005549877,0.0001451295,0.0004120271,0.00001285541],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9592733,0.001643621,0.001808847,0.0007149134,0.001357585,0.029441,0.002079875,0.0003010301,0.003379791],"genre_scores_gemma":[0.9355537,0.00157327,0.005303257,0.002058612,0.001020047,0.04309697,0.00163771,0.00006732591,0.009689122],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008409692,"threshold_uncertainty_score":0.02813315,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04364078429734954,"score_gpt":0.3781696680219289,"score_spread":0.3345288837245793,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}