{"id":"W2563325642","doi":"10.1093/ofid/ofw172.973","title":"A Phase I Randomized, Observer-Blind, Controlled, Dose Escalation Trial of the Safety and Tolerability of Two Intramuscular Doses of DPX-RSV(A), a Respiratory Syncytial Virus (RSV) Vaccine Containing RSV SH Antigen and a Novel Adjuvant DepoVax, or SH Antigen Co-administered With Aluminum Hydroxide, or Placebo to Healthy Adults ≥50–64 Years of Age","year":2016,"lang":"en","type":"article","venue":"Open Forum Infectious Diseases","topic":"Respiratory viral infections research","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Immunovaccine (Canada); Nova Scotia Health Authority; Izaak Walton Killam Health Centre; Dalhousie University","funders":"","keywords":"Medicine; Tolerability; Palivizumab; Virology; Adverse effect; Randomized controlled trial; Virus; Respiratory system; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002212698,0.0004191597,0.00281766,0.0004017038,0.000204301,0.00006052177,0.0003255476,0.0001707216,0.0001238554],"category_scores_gemma":[0.004949204,0.0002354283,0.0003604628,0.0006469174,0.0007492824,0.0004130559,0.000365671,0.0002144704,0.000001184799],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001617086,"about_ca_system_score_gemma":0.001410641,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002210996,"about_ca_topic_score_gemma":0.003864021,"domain_scores_codex":[0.9948846,0.001100675,0.002067564,0.0006930445,0.0007636219,0.0004904899],"domain_scores_gemma":[0.9948866,0.001942365,0.001250999,0.0009047749,0.0005722693,0.0004429297],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8730818,0.003379107,0.09467368,0.0004358715,0.0008018805,0.00003387969,0.0002601511,0.0000290596,0.01902277,0.00007635163,0.00002441826,0.008181018],"study_design_scores_gemma":[0.9004894,0.02737522,0.06134568,0.00133905,0.0006168333,0.00003817064,0.0002302117,0.0001909739,0.007807485,0.00003354015,0.0002302528,0.0003031178],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9839549,0.000368924,0.000603683,0.0001625529,0.000111938,0.01406444,0.0005733949,0.00003123818,0.0001289006],"genre_scores_gemma":[0.9987687,0.0002047437,0.0001166864,0.00021141,0.00006758057,0.0005235211,0.00001896009,0.00005544225,0.00003288167],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03332799,"threshold_uncertainty_score":0.9600489,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04364078429734954,"score_gpt":0.3781696680219289,"score_spread":0.3345288837245793,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}