{"id":"W2563362161","doi":"10.1111/dom.12864","title":"The effects of atrasentan on urinary metabolites in patients with type 2 diabetes and nephropathy","year":2016,"lang":"en","type":"article","venue":"Diabetes Obesity and Metabolism","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Health Science Centre","funders":"National Institutes of Health; Novo Nordisk; Kyowa Hakko Kirin; Boehringer Ingelheim; AstraZeneca; Amgen","keywords":"Medicine; Urology; Type 2 diabetes; Albuminuria; Placebo; Diabetic nephropathy; Metabolite; Diabetes mellitus; Population; Internal medicine; Renal function; Urine; Urinary system; Gastroenterology; Endocrinology; Pharmacology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001916633,0.000509788,0.001972461,0.0002510288,0.0002246403,0.0004889996,0.0002442657,0.0003874386,0.0009832053],"category_scores_gemma":[0.001930734,0.0002070491,0.001473441,0.0003110002,0.0001956976,0.0003249584,0.0002929008,0.0007970265,0.000106248],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002702454,"about_ca_system_score_gemma":0.0004145077,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005683426,"about_ca_topic_score_gemma":0.001723638,"domain_scores_codex":[0.999128,0.0004891522,0.00009561716,0.0001112161,0.00009871534,0.00007719144],"domain_scores_gemma":[0.9986734,0.0004704363,0.0004577585,0.0000727573,0.0001080806,0.0002175453],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.5195208,0.009137728,0.2634881,0.001511387,0.009041555,0.0003794439,0.0003124153,0.002124581,0.03924017,0.0001068644,0.0004709496,0.1546661],"study_design_scores_gemma":[0.02037154,0.1669512,0.7935753,0.00009820179,0.005528017,0.0003403453,0.0001813704,0.001574987,0.00909884,0.0001875747,0.002037679,0.00005498559],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944031,0.004505297,0.0001576826,0.00008807006,0.00002827407,0.00006226329,0.0001187044,0.0000107725,0.0006257819],"genre_scores_gemma":[0.9978515,0.001010897,0.0005014543,0.0001357232,0.00003786142,0.00002975738,0.0001545231,0.000002899379,0.0002753412],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001972461,"threshold_uncertainty_score":0.01013625,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.001673696290288489,"score_gpt":0.1643762295613279,"score_spread":0.1627025332710394,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}