{"id":"W2563374801","doi":"10.1158/1538-7445.am2015-4762","title":"Abstract 4762: ITPKA expression in lung and other cancers, regulated via gene body methylation, functions as an oncogene","year":2015,"lang":"en","type":"article","venue":"Cancer Research","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Oncogene; Methylation; DNA methylation; Cancer research; Lung cancer; Biology; CpG site; Cancer; Gene expression; Gene; Medicine; Pathology; Cell cycle; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007089767,0.0002062688,0.0001709786,0.0003187535,0.0001777185,0.0002189484,0.0001307899,0.0002113908,0.004028058],"category_scores_gemma":[0.00009879192,0.0001057118,0.0001742964,0.00027883,0.0001702676,0.0001907575,0.0001826914,0.0003387465,0.0008875207],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002422421,"about_ca_system_score_gemma":0.0002091986,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00071409,"about_ca_topic_score_gemma":0.0007228057,"domain_scores_codex":[0.9999202,0.000006176397,0.000006036475,0.00002597109,0.00002610553,0.00001546943],"domain_scores_gemma":[0.9999483,0.00000464107,0.00001458729,0.000004854383,0.000009828088,0.00001789156],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001066081,0.00001269651,0.001382966,0.00007860189,0.000006594178,0.0001221048,0.00001541196,0.00003291441,0.994499,0.000152606,0.0002587973,0.003331754],"study_design_scores_gemma":[0.00003499935,0.0003231645,0.08535519,0.00001660869,0.00004636784,0.001533888,0.0000661299,0.0009576957,0.900205,0.0002644106,0.01118563,0.00001095565],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9825733,0.005791449,0.00383418,0.000348897,0.0001692196,0.00004445235,0.0016046,0.0002533238,0.005380481],"genre_scores_gemma":[0.9802106,0.001921908,0.001393702,0.00009650063,0.00004769493,0.00005841989,0.001311289,0.00002381416,0.0149361],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004028058,"threshold_uncertainty_score":0.01347518,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06475764035287425,"score_gpt":0.4076910213119694,"score_spread":0.3429333809590951,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}