{"id":"W2563684930","doi":"10.1158/1538-7445.am2015-4960","title":"Abstract 4960: ERp46 (thioredoxin domain-containing protein 5, TXND5) promotes prostate cancer growth in vitro and in vivo","year":2015,"lang":"en","type":"article","venue":"Cancer Research","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Prostate cancer; Prostate; Gene knockdown; Cancer research; In vivo; PCA3; LNCaP; Biology; Cancer; Pathology; Medicine; Cell culture; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001417924,0.0002720519,0.0002628047,0.0002417313,0.0001387602,0.0002685348,0.0001459408,0.0002206556,0.00516576],"category_scores_gemma":[0.00007587979,0.0001308655,0.0002824781,0.0002166213,0.0001284811,0.0001361208,0.0002061697,0.000649109,0.001402602],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001873753,"about_ca_system_score_gemma":0.0001696773,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008959088,"about_ca_topic_score_gemma":0.0005687453,"domain_scores_codex":[0.9998463,0.00002187674,0.00001189288,0.00002938278,0.00005611635,0.00003437679],"domain_scores_gemma":[0.9999247,0.00001049576,0.00001427088,0.00001017851,0.00000986476,0.00003045226],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002369779,0.0001042582,0.0002620663,0.00005624285,0.00001097726,0.00005132777,0.00000700078,0.00007444709,0.9964195,0.00004778739,0.0004656486,0.002263868],"study_design_scores_gemma":[0.00004409198,0.001179327,0.01458877,0.000008435583,0.00003101661,0.0004716662,0.00003092847,0.001612682,0.97615,0.00003693574,0.005839651,0.000006365873],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.981716,0.006812398,0.003403111,0.0004365564,0.0002029402,0.00003375408,0.002123016,0.0004205354,0.004851746],"genre_scores_gemma":[0.9854455,0.00179343,0.001315038,0.0001651434,0.00002936462,0.00003237278,0.002982192,0.00003725817,0.008199754],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00516576,"threshold_uncertainty_score":0.01728117,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03079647286308078,"score_gpt":0.3457061690626303,"score_spread":0.3149096961995495,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}