{"id":"W2563817914","doi":"10.1139/gen-2016-0165","title":"Overexpression of <i>Buffy</i> enhances the loss of <i>parkin</i> and suppresses the loss of <i>Pink1</i> phenotypes in <i>Drosophila</i>","year":2016,"lang":"en","type":"article","venue":"Genome","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"","keywords":"Parkin; PINK1; Biology; Phenotype; RNA interference; Cell biology; Genetics; Gene silencing; Mitochondrion; Gene; Mitophagy; Parkinson's disease; Autophagy; RNA; Disease; Internal medicine; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009280132,0.0003767699,0.0001912036,0.0002308544,0.0001591995,0.0002822786,0.0002291658,0.0003063091,0.001388684],"category_scores_gemma":[0.0000641136,0.0001790923,0.0002552178,0.0001548965,0.0002619547,0.0001706248,0.0002824253,0.0006443122,0.000443341],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003400117,"about_ca_system_score_gemma":0.0001629238,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001412336,"about_ca_topic_score_gemma":0.002442238,"domain_scores_codex":[0.9998652,0.00001361203,0.00001852498,0.0000419945,0.00003475068,0.00002594718],"domain_scores_gemma":[0.9998734,0.00001651857,0.00004728249,0.00001071825,0.000007578117,0.00004434584],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002831321,0.000008927467,0.00005601982,0.00001725385,0.00000246999,0.00002394918,0.000004834608,0.00002717687,0.999559,0.0000356333,0.00001909697,0.000217281],"study_design_scores_gemma":[0.000008760235,0.00007858216,0.004011078,0.0000052718,0.00001046134,0.0001145778,0.00001414067,0.0004824557,0.9933869,0.000013942,0.001869114,0.000004838797],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928365,0.0009595623,0.00220425,0.0001074604,0.00002301041,0.0000336745,0.001362871,0.000144288,0.00232842],"genre_scores_gemma":[0.9866101,0.0008111373,0.003411594,0.00009829144,0.000008875044,0.00004684151,0.002038152,0.0001078814,0.006867184],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001412336,"threshold_uncertainty_score":0.004645646,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01108514522205784,"score_gpt":0.24174553537854,"score_spread":0.2306603901564822,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}