{"id":"W2564089462","doi":"10.1128/iai.00781-16","title":"The Lyme Disease Pathogen Borrelia burgdorferi Infects Murine Bone and Induces Trabecular Bone Loss","year":2016,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Parasites and Host Interactions","field":"Immunology and Microbiology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; University of Toronto","funders":"Canadian Institutes of Health Research; University of Toronto; Canada Foundation for Innovation; Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Borrelia burgdorferi; Osteoblast; Osteoclast; Biology; Lyme disease; Bone disease; Bone mineral; Osteoid; Borrelia Burgdorferi Infection; Immunology; Osteoporosis; Anatomy; Endocrinology; In vitro; Antibody; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003374011,0.0007196053,0.0004452851,0.001221626,0.0002660265,0.0003379619,0.000364741,0.0007171555,0.001608505],"category_scores_gemma":[0.0001291755,0.0006005802,0.0003901614,0.0004096996,0.0004924395,0.0002313315,0.0003355514,0.0009218701,0.000442218],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003323881,"about_ca_system_score_gemma":0.0002506624,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009716724,"about_ca_topic_score_gemma":0.002035848,"domain_scores_codex":[0.999525,0.00008473372,0.00003322397,0.00009995495,0.0001307092,0.0001263715],"domain_scores_gemma":[0.9996777,0.00003775448,0.0001126562,0.00003247753,0.00002943301,0.0001100617],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004370307,0.000155849,0.0005574704,0.00004069536,0.00001002623,0.00004920346,0.00002194056,0.00009640711,0.9977724,0.00006503974,0.00003438986,0.0007596802],"study_design_scores_gemma":[0.0003796229,0.006949361,0.02498056,0.00005298146,0.00008264974,0.0006427513,0.000166651,0.00254617,0.9605973,0.0002670423,0.003310181,0.00002473458],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939614,0.002577608,0.001761284,0.00009725198,0.00003018077,0.00003348375,0.0006029886,0.0001054758,0.0008304152],"genre_scores_gemma":[0.9913424,0.00171427,0.002688806,0.00009884185,0.00001525242,0.00009815079,0.0007070005,0.00004523234,0.003289961],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001608505,"threshold_uncertainty_score":0.005380929,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009995167382035354,"score_gpt":0.2568718432091113,"score_spread":0.246876675827076,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}