{"id":"W2564089462","doi":"10.1128/iai.00781-16","title":"The Lyme Disease Pathogen Borrelia burgdorferi Infects Murine Bone and Induces Trabecular Bone Loss","year":2016,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Parasites and Host Interactions","field":"Immunology and Microbiology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; University of Toronto","funders":"Canadian Institutes of Health Research; University of Toronto; Canada Foundation for Innovation; Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Borrelia burgdorferi; Osteoblast; Osteoclast; Biology; Lyme disease; Bone disease; Bone mineral; Osteoid; Borrelia Burgdorferi Infection; Immunology; Osteoporosis; Anatomy; Endocrinology; In vitro; Antibody; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002359557,0.0001548907,0.0001693545,0.00007411462,0.000843616,0.00004953691,0.00004840355,0.0001168407,0.0001793923],"category_scores_gemma":[0.0002072413,0.00009180058,0.00006751836,0.00008566946,0.0003431275,0.000201924,0.00009487326,0.0002363736,0.0001162962],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000024676,"about_ca_system_score_gemma":0.00002931992,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007130778,"about_ca_topic_score_gemma":0.0001335647,"domain_scores_codex":[0.9991307,0.0002238563,0.0002098435,0.0001762259,0.00002599572,0.0002334178],"domain_scores_gemma":[0.9992856,0.0002335854,0.00009551821,0.0002603792,0.00006582269,0.00005908338],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0004417227,0.0002885776,0.08647577,0.00002210128,0.0002125806,0.0000154838,0.0002818411,5.246347e-7,0.853937,0.001805134,0.0009097626,0.05560952],"study_design_scores_gemma":[0.001220091,0.000233159,0.7935881,0.00006690927,0.00007118411,0.0002687548,0.00004856245,0.000001913398,0.01336874,0.0005676873,0.1903589,0.0002059993],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923559,0.00540884,0.00008487957,0.0008925113,0.0006034815,0.000149904,0.00004721461,0.00007016992,0.0003870803],"genre_scores_gemma":[0.9933463,0.004925985,0.000002145522,0.0001204556,0.00003602024,0.00003107218,0.00002894636,0.00001027725,0.001498775],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8405682,"threshold_uncertainty_score":0.6488498,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009995167382035354,"score_gpt":0.2568718432091113,"score_spread":0.246876675827076,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}