{"id":"W2564417513","doi":"10.1182/blood.v112.11.2460.2460","title":"New Candidate Regulators of Hematopoietic Stem Cells Identified from Transcriptional Comparisons of Highly Purified Populations of Longterm Repopulating Cells with Markedly Different in Vivo Self-Renewal Activities","year":2008,"lang":"en","type":"article","venue":"Blood","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Leukemia & Lymphoma Society of Canada; Canada's Michael Smith Genome Sciences Centre; BC Cancer Agency","funders":"","keywords":"Biology; Haematopoiesis; Stem cell; In vivo; BMI1; Bone marrow; Immunology; Molecular biology; Cell biology; Cancer research; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002057999,0.0002123384,0.000226037,0.0004249277,0.000112324,0.0003877872,0.0001435098,0.0001674909,0.001610828],"category_scores_gemma":[0.0001668496,0.0001304322,0.0002226799,0.000214461,0.0002118522,0.0001337951,0.0002263782,0.0003843538,0.0004447991],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001474308,"about_ca_system_score_gemma":0.0001297828,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000173029,"about_ca_topic_score_gemma":0.000372083,"domain_scores_codex":[0.9998047,0.000019781,0.00001795747,0.00006347506,0.00005265686,0.00004142598],"domain_scores_gemma":[0.9998392,0.00004069527,0.00004652579,0.00001331534,0.00002334521,0.00003691317],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002951161,0.000004652258,0.0005615915,0.000008164211,0.000001617167,0.000004890715,0.00001201258,0.000006160478,0.9989604,0.0000176129,0.000004143549,0.0003891469],"study_design_scores_gemma":[0.00001464129,0.000327414,0.1116686,0.00001032848,0.00003464326,0.0001806563,0.000103432,0.0007425069,0.8855719,0.00005912483,0.001281253,0.000005641233],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942107,0.0005910074,0.00384585,0.0000230245,0.000007773858,0.00003084915,0.00069913,0.00004361685,0.0005480562],"genre_scores_gemma":[0.9907844,0.0002970354,0.004505567,0.00007563931,0.0000170251,0.0001205732,0.002578482,0.00003315055,0.001588099],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001610828,"threshold_uncertainty_score":0.005388737,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02257887963297128,"score_gpt":0.2350487942322783,"score_spread":0.212469914599307,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}