{"id":"W2564710210","doi":"10.1158/1538-7445.am2015-3381","title":"Abstract 3381: Standardizing the analysis of Ki-67 immunohistochemical assays","year":2015,"lang":"en","type":"article","venue":"Cancer Research","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; University of Toronto","funders":"","keywords":"Medicine; Tissue microarray; Breast cancer; Significant difference; Pathology; Immunohistochemistry; Internal medicine; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.039133,0.0009716506,0.0008313041,0.002630936,0.000938268,0.001910388,0.00209346,0.001234226,0.001768772],"category_scores_gemma":[0.05890452,0.0005591103,0.0005399112,0.001735804,0.001173345,0.001079281,0.002328276,0.000924708,0.001455978],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001134782,"about_ca_system_score_gemma":0.001198266,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001747049,"about_ca_topic_score_gemma":0.002747557,"domain_scores_codex":[0.9675335,0.01171507,0.003336978,0.005062325,0.01166792,0.000684204],"domain_scores_gemma":[0.9552643,0.01313049,0.003224501,0.008693885,0.01921115,0.0004756064],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001655797,0.0005696834,0.1503168,0.0009073127,0.0002143807,0.0001409816,0.001632179,0.004491466,0.5646174,0.001274768,0.003712805,0.2704664],"study_design_scores_gemma":[0.0001731581,0.002279841,0.4395628,0.0002715856,0.000329585,0.001010745,0.0009306871,0.04231576,0.489891,0.002125057,0.02085431,0.0002555792],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.5786346,0.001912431,0.4071203,0.0004418184,0.0004880048,0.001766993,0.001043574,0.002677188,0.005915046],"genre_scores_gemma":[0.5256241,0.0004803651,0.4677987,0.0002175151,0.0001350931,0.00169648,0.00203455,0.0006106473,0.001402581],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.039133,"threshold_uncertainty_score":0.2069575,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1032175581477811,"score_gpt":0.4375328179851265,"score_spread":0.3343152598373454,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}