{"id":"W2564800078","doi":"10.14670/hh-11-862","title":"Targeting exogenous β-Defensin to the endolysosomal compartment via a vehicle guided system.","year":2017,"lang":"en","type":"article","venue":"PubMed","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Endosome; LAMP1; Cell biology; Endocytosis; Biology; Confocal microscopy; Beta defensin; Transfection; Fusion protein; Peptide; Defensin; Chemistry; Biochemistry; Receptor; Recombinant DNA; Gene; Intracellular","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001755302,0.0004374837,0.0002273594,0.00019229,0.0001645897,0.0005191136,0.000369808,0.0005728989,0.000577473],"category_scores_gemma":[0.0000830021,0.0001519677,0.0002724594,0.000100414,0.0002769592,0.000284579,0.0003197229,0.0005281518,0.0005607845],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000507157,"about_ca_system_score_gemma":0.000394098,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006952907,"about_ca_topic_score_gemma":0.000806452,"domain_scores_codex":[0.9998697,0.00002073317,0.000008729782,0.00003306238,0.00003712853,0.00003071911],"domain_scores_gemma":[0.9999262,0.000008988235,0.00002447565,0.000009719118,0.00001276341,0.00001785006],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002543812,0.00001551754,0.00005534102,0.00004374672,0.000006024172,0.00004608727,0.00001505824,0.00007132814,0.9976816,0.0004996796,0.00007921318,0.001460823],"study_design_scores_gemma":[0.000009211853,0.0001369618,0.0002891294,0.000005750502,0.00001143141,0.0002268427,0.0000150986,0.001539186,0.9914819,0.00005042394,0.006227977,0.000006009194],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9155266,0.003352416,0.07375377,0.0004949445,0.0002157546,0.0003903812,0.0006307453,0.0006527295,0.004982694],"genre_scores_gemma":[0.9428291,0.00203408,0.04509087,0.0002334577,0.00001772216,0.0002084274,0.0007422539,0.0000857091,0.008758334],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006952907,"threshold_uncertainty_score":0.003679752,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02893420453650838,"score_gpt":0.2231830129161457,"score_spread":0.1942488083796373,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}