{"id":"W2565124624","doi":"10.1158/1538-7445.am2015-2123","title":"Abstract 2123: Protein synthesis and its control in cancer development, progression and treatment","year":2015,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Translation (biology); Cancer; PI3K/AKT/mTOR pathway; EIF4E; Biology; MAPK/ERK pathway; Protein biosynthesis; Signal transduction; Cancer research; Genetics; Messenger RNA; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004762117,0.0008898388,0.0008104595,0.001413296,0.000345926,0.002144126,0.000619802,0.001216675,0.01714055],"category_scores_gemma":[0.0007034768,0.0002194312,0.0003576105,0.001119587,0.0006458994,0.000982899,0.0006322092,0.002598065,0.01314068],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001359039,"about_ca_system_score_gemma":0.0008970308,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001244653,"about_ca_topic_score_gemma":0.001980271,"domain_scores_codex":[0.9997229,0.00006030097,0.0000283618,0.00005038906,0.0001186371,0.00001943404],"domain_scores_gemma":[0.9997179,0.0001003097,0.00003433133,0.00001187583,0.00008846489,0.00004716967],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002445133,0.00008014022,0.000213982,0.00198847,0.00003780257,0.000158478,0.00007353631,0.000482291,0.003278459,0.009143935,0.529331,0.4549674],"study_design_scores_gemma":[0.00001666008,0.0001243453,0.001027003,0.00096666,0.00002217858,0.0004959732,0.00005526009,0.0002075941,0.0008747107,0.005138322,0.9910562,0.0000149575],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"review","genre_gemma":"other","genre_scores_codex":[0.0006002845,0.9413271,0.001042422,0.01272301,0.01993827,0.00002357988,0.0002136509,0.0001050446,0.02402668],"genre_scores_gemma":[0.006709042,0.8586298,0.001240171,0.005927339,0.03065382,0.00005171303,0.0004972119,0.0000662047,0.09622476],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.01714055,"threshold_uncertainty_score":0.05734092,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0852366454917909,"score_gpt":0.4008906571344856,"score_spread":0.3156540116426947,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}