{"id":"W2565128187","doi":"10.1158/1538-7445.am2015-2853","title":"Abstract 2853: Investigating DNAPK as a biomarker and a novel therapeutic target in aggressive prostate cancer","year":2015,"lang":"en","type":"article","venue":"Cancer Research","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Genome British Columbia","funders":"","keywords":"LNCaP; DU145; Prostate cancer; Cancer research; Wnt signaling pathway; Kinase; Cancer; Androgen receptor; Medicine; Signal transduction; Biology; Internal medicine; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002463881,0.0004486114,0.000375471,0.0004128937,0.00016835,0.0004856785,0.0001786038,0.0003107488,0.002246469],"category_scores_gemma":[0.0001487758,0.0001195072,0.0002226746,0.0003894071,0.0002357298,0.0002704887,0.000164263,0.0005061498,0.000488817],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005464408,"about_ca_system_score_gemma":0.0005628765,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007649708,"about_ca_topic_score_gemma":0.001620456,"domain_scores_codex":[0.9998982,0.000015834,0.000007670084,0.00002397346,0.00003009164,0.00002437109],"domain_scores_gemma":[0.9999003,0.00001341017,0.00003070657,0.000004635168,0.0000165221,0.00003425739],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001067065,0.0001855448,0.009930145,0.0003855611,0.00006345753,0.0001080809,0.00002469351,0.0004332782,0.975951,0.0001274503,0.0003165496,0.01140725],"study_design_scores_gemma":[0.0002028365,0.003842676,0.1203604,0.00005678243,0.0002378729,0.001625903,0.0001117256,0.003152327,0.8621433,0.0003018552,0.00793738,0.00002685399],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.9888096,0.006863773,0.001350845,0.0002318579,0.00003705992,0.00008511674,0.001151772,0.00006022996,0.001409768],"genre_scores_gemma":[0.9911036,0.002568723,0.002629908,0.0001138538,0.00002725691,0.00004549453,0.001339193,0.000007161483,0.002164687],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.002246469,"threshold_uncertainty_score":0.007515192,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2175423079491852,"score_gpt":0.4718878309227099,"score_spread":0.2543455229735246,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}