{"id":"W2565136629","doi":"10.1182/blood.v120.21.3274.3274","title":"Ivig Negatively Regulates LPS-Induced Monocytes Activation Through a Microrna-146a Related Mechanism","year":2012,"lang":"en","type":"article","venue":"Blood","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Héma-Québec","funders":"","keywords":"Innate immune system; Biology; Cell biology; Gene silencing; Immune system; Acquired immune system; microRNA; Inflammation; RNA interference; Signal transduction; Proinflammatory cytokine; Immunology; RNA; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001683051,0.0003400331,0.0003343047,0.0002738522,0.0001375587,0.0003617028,0.0001910739,0.0002407806,0.002253659],"category_scores_gemma":[0.0001481397,0.0001239517,0.0003284897,0.0001321402,0.0001934558,0.0000915929,0.0001919606,0.0005248495,0.0007664451],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002242324,"about_ca_system_score_gemma":0.0001795405,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001794794,"about_ca_topic_score_gemma":0.0002497218,"domain_scores_codex":[0.9998145,0.00004126484,0.00001913011,0.00003632494,0.0000403429,0.00004852422],"domain_scores_gemma":[0.9998897,0.00001393792,0.00004745918,0.000009736761,0.00001438335,0.00002475273],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004525885,0.00005937845,0.0004663207,0.0001581377,0.00001661389,0.0001568621,0.00001635193,0.00004851063,0.9960251,0.0001230247,0.000201659,0.00227547],"study_design_scores_gemma":[0.0001340559,0.001172236,0.03068751,0.00005076264,0.0001095498,0.0009399623,0.0000828327,0.001832927,0.9509451,0.0002170495,0.01381419,0.00001382685],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9659989,0.0173829,0.007591602,0.0004025232,0.0003567849,0.0001507386,0.001259655,0.0004211092,0.006435844],"genre_scores_gemma":[0.9868056,0.003044287,0.003827243,0.0002973768,0.00007259002,0.0001701879,0.00117115,0.00005889399,0.004552794],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002253659,"threshold_uncertainty_score":0.007539213,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01649766219875759,"score_gpt":0.2469848713279726,"score_spread":0.230487209129215,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}