{"id":"W2565251648","doi":"10.1074/jbc.m116.757864","title":"A Late G1 Lipid Checkpoint That Is Dysregulated in Clear Cell Renal Carcinoma Cells","year":2016,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Genetic and Kidney Cyst Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Cancer Institute; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Cell biology; Cell cycle checkpoint; Endoplasmic reticulum; Cell cycle; PI3K/AKT/mTOR pathway; Biology; Lipid droplet; Chemistry; Cell; Biochemistry; Signal transduction","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001045983,0.0002287046,0.0002861204,0.0006060234,0.0003974281,0.0004823697,0.0001771803,0.0003422391,0.002477438],"category_scores_gemma":[0.0001599156,0.0001345548,0.0002144955,0.0004260216,0.0002014893,0.0002946446,0.0002087059,0.0004835644,0.0007087025],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006543298,"about_ca_system_score_gemma":0.0006238335,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002606513,"about_ca_topic_score_gemma":0.00303191,"domain_scores_codex":[0.9998915,0.0000105395,0.00001270705,0.0000258612,0.00003656277,0.0000226767],"domain_scores_gemma":[0.9998834,0.000009241955,0.00003055451,0.0000137705,0.0000225298,0.00004049483],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000283559,0.00003527914,0.001472722,0.0000537718,0.00001000318,0.0002830492,0.00004052388,0.0001005692,0.9942352,0.0003626047,0.0002882602,0.002834472],"study_design_scores_gemma":[0.0000792076,0.0003769454,0.06568681,0.00001724405,0.0000373914,0.001729848,0.0002079803,0.001376573,0.9145041,0.0003801506,0.01558658,0.00001712215],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.989309,0.00401068,0.001560207,0.000391377,0.00008514721,0.00003618991,0.001432941,0.0002449357,0.002929545],"genre_scores_gemma":[0.9933821,0.001315866,0.0008150218,0.0001023384,0.00001174521,0.00004336215,0.0008697679,0.00002598722,0.003433837],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002606513,"threshold_uncertainty_score":0.008287847,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01326378891619533,"score_gpt":0.2161848060591594,"score_spread":0.202921017142964,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}