{"id":"W2565253719","doi":"10.1016/j.mad.2016.12.011","title":"Autophagy induction reduces telomerase activity in HeLa cells","year":2016,"lang":"en","type":"article","venue":"Mechanisms of Ageing and Development","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Telomerase; HeLa; Autophagy; Telomere; Biology; Cell biology; Cell culture; Cancer research; Molecular biology; Virology; Chemistry; Genetics; DNA; Gene; Apoptosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001676539,0.0002033161,0.0005450914,0.0002950528,0.0003196695,0.0004279228,0.0001743996,0.0002942154,0.002178009],"category_scores_gemma":[0.0001864994,0.0001569056,0.0004331715,0.0002269046,0.0002050437,0.0002470484,0.0002129669,0.0005813844,0.000491226],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000382264,"about_ca_system_score_gemma":0.0004194872,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001241472,"about_ca_topic_score_gemma":0.001681388,"domain_scores_codex":[0.9998263,0.00003055503,0.00003047756,0.00003177845,0.00002694688,0.0000539711],"domain_scores_gemma":[0.999864,0.00004145053,0.00002138398,0.00002668113,0.00001660993,0.00003001477],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004827921,0.00004607926,0.0001890666,0.00006528213,0.00001506077,0.00006611953,0.00003758732,0.00004177717,0.9973295,0.0001467232,0.0002069449,0.00137306],"study_design_scores_gemma":[0.00003046735,0.0002678843,0.002992774,0.00000988652,0.00002793648,0.0001384622,0.00004775703,0.0003768096,0.9926453,0.00007410083,0.00338339,0.000005368815],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9883876,0.0052985,0.001131089,0.0003819399,0.0001454596,0.00002231472,0.001185968,0.0001596996,0.00328727],"genre_scores_gemma":[0.9911358,0.001970253,0.0009533595,0.0001178854,0.0000379077,0.00003793482,0.001174448,0.00003694079,0.004535355],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002178009,"threshold_uncertainty_score":0.007286191,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01951095190002716,"score_gpt":0.2449244735921697,"score_spread":0.2254135216921426,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}