{"id":"W2565253719","doi":"10.1016/j.mad.2016.12.011","title":"Autophagy induction reduces telomerase activity in HeLa cells","year":2016,"lang":"en","type":"article","venue":"Mechanisms of Ageing and Development","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Telomerase; HeLa; Autophagy; Telomere; Biology; Cell biology; Cell culture; Cancer research; Molecular biology; Virology; Chemistry; Genetics; DNA; Gene; Apoptosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003514462,0.0001671131,0.0003192898,0.0002547217,0.00007084494,0.00001001144,0.00005920703,0.0001040011,0.00006205535],"category_scores_gemma":[0.00005018851,0.000118545,0.00002942713,0.0001678742,0.00005193514,0.000123809,0.00005373733,0.0001046691,0.00001572941],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009506515,"about_ca_system_score_gemma":0.0001795989,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008827174,"about_ca_topic_score_gemma":0.00002363859,"domain_scores_codex":[0.9988028,0.00004014032,0.0003023363,0.0003273829,0.0002627946,0.0002644787],"domain_scores_gemma":[0.9995018,0.00005579508,0.0001069296,0.0001557773,0.00005235769,0.0001273605],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009859374,0.000114667,0.0002737895,0.00006538622,0.00001728268,0.00007542418,0.0005485395,4.806923e-7,0.7729479,0.0001110025,0.00002675857,0.2257201],"study_design_scores_gemma":[0.0009515319,0.0001190629,0.06054159,0.0003796927,0.000008703962,0.00002420014,0.000206058,0.000005587987,0.9366623,0.0003313622,0.0006141927,0.0001557745],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939411,0.0001015505,0.004951827,0.0003486449,0.00025105,0.0001995606,0.00000243924,0.00005155457,0.000152252],"genre_scores_gemma":[0.9857759,0.0001515052,0.01321614,0.00007403974,0.00003136544,0.0000162035,0.000002025451,0.0000150643,0.0007177294],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2255644,"threshold_uncertainty_score":0.4834127,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01951095190002716,"score_gpt":0.2449244735921697,"score_spread":0.2254135216921426,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}