{"id":"W2565738065","doi":"10.1158/1538-7445.am2015-395","title":"Abstract 395: Effect of pantoprazole to enhance activity of docetaxel against human tumor xenografts by inhibiting autophagy","year":2015,"lang":"en","type":"article","venue":"Cancer Research","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Autophagy; Docetaxel; Pantoprazole; Apoptosis; Chemistry; Pharmacology; Programmed cell death; Cancer research; Chemotherapy; Biology; Medicine; Internal medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000530722,0.000290269,0.0002196403,0.0001663529,0.0001242865,0.0001425968,0.0001591048,0.0001724727,0.001629422],"category_scores_gemma":[0.00006040989,0.00007958728,0.0001621303,0.0001606255,0.0001261019,0.0001004263,0.00008972407,0.0003880504,0.0002614858],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003597228,"about_ca_system_score_gemma":0.0003063044,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002890172,"about_ca_topic_score_gemma":0.005020285,"domain_scores_codex":[0.9999442,0.000009006656,0.000005718376,0.00001149873,0.00001551057,0.00001409208],"domain_scores_gemma":[0.9999558,0.0000101617,0.00000770151,0.000005662956,0.000005901997,0.0000147005],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009911604,0.0003291846,0.0002873275,0.00007326653,0.00001302056,0.00006913904,0.000017856,0.0001893784,0.9931339,0.00004915862,0.0003345929,0.004511958],"study_design_scores_gemma":[0.0001067853,0.003671461,0.003546299,0.00000519572,0.00002769908,0.0001945289,0.0000128876,0.0006380596,0.9899172,0.00001176983,0.001863709,0.000004282532],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964023,0.001230542,0.0003735929,0.00008753073,0.00004480945,0.00003775566,0.0004692438,0.00006971309,0.001284575],"genre_scores_gemma":[0.9959044,0.0006190032,0.0007852638,0.00002937622,0.000009646934,0.00002510607,0.0006595982,0.00001448473,0.001953193],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002890172,"threshold_uncertainty_score":0.005746722,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06045847471580709,"score_gpt":0.4611386929891779,"score_spread":0.4006802182733708,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}