{"id":"W2565898139","doi":"10.1016/s1525-0016(16)33363-9","title":"555. Development of a Post-Exposure Treatment for Ebola Virus Infections Based on AAV Vectors and Zmapp Antibody Cocktail","year":2016,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"Viral Infections and Outbreaks Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada; Public Health Agency of Canada; McGill University; Université Laval","funders":"","keywords":"Antibody; Virology; Ebola virus; HEK 293 cells; Transfection; Virus; Genetic enhancement; Recombinant DNA; Neutralizing antibody; Cell culture; Biology; In vivo; Gene; Medicine; Immunology; Biotechnology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001246572,0.0001542255,0.0002283501,0.0002037924,0.0001316212,0.00001230467,0.000032742,0.00007713843,0.0001023106],"category_scores_gemma":[0.00002982184,0.00009166905,0.0001211458,0.0001356288,0.00006299552,0.00002491667,0.00000918843,0.00004807976,0.00001145677],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001063327,"about_ca_system_score_gemma":0.0001974425,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006635761,"about_ca_topic_score_gemma":0.0000243549,"domain_scores_codex":[0.9991618,0.00004703735,0.0001899527,0.0002212428,0.0001739625,0.0002060045],"domain_scores_gemma":[0.9993978,0.00007606026,0.00004487611,0.0002122488,0.0001642763,0.0001047673],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005657349,0.0006997048,0.003688223,0.0000191814,0.0001635583,0.000008278081,0.0001112112,0.000004713027,0.8825164,0.00007334999,0.00001747116,0.1121321],"study_design_scores_gemma":[0.006942253,0.007291303,0.02622269,0.0001003899,0.00003019992,0.000009855861,0.00001917993,0.00009313862,0.9296228,0.00002357846,0.02950576,0.000138905],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9810511,0.0002589116,0.01667489,0.0006594515,0.00005061038,0.0008552714,0.00003157355,0.00003594744,0.0003822433],"genre_scores_gemma":[0.99817,0.0001722493,0.0008139651,0.0002621613,0.00002717006,0.0001671958,0.00003359416,0.00002786507,0.0003258161],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1119932,"threshold_uncertainty_score":0.3738155,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02710315176680765,"score_gpt":0.3430009703773769,"score_spread":0.3158978186105692,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}