{"id":"W2566072324","doi":"10.1002/ana.24840","title":"Genetic variation at 16q24.2 is associated with small vessel stroke","year":2016,"lang":"en","type":"article","venue":"Annals of Neurology","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":89,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Heart, Lung, and Blood Institute; National Institute on Aging; Medical Research Council; National Institutes of Health; Vlaamse regering; Fonds Wetenschappelijk Onderzoek; Deutsche Forschungsgemeinschaft; King's College London; California Department of Fish and Game; University of Cambridge; Cambridge University Hospitals; Stroke Association; National Institute of Neurological Disorders and Stroke; National Institute for Health and Care Research; Wellcome Trust; H2020 European Research Council; South London and Maudsley NHS Foundation Trust; Wellcome","keywords":"Genome-wide association study; Odds ratio; Stroke (engine); Medicine; Single-nucleotide polymorphism; Intracerebral hemorrhage; Population; Confidence interval; Internal medicine; Genetic association; Biology; Genetics; Genotype; Gene; Subarachnoid hemorrhage","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001008603,0.00010352,0.0002443386,0.00007430735,0.00002447267,0.000002061929,0.00006831354,0.0001093027,0.0003380434],"category_scores_gemma":[0.0001316148,0.00006887301,0.00009005018,0.00008488194,0.00008706067,0.00001416126,0.00003324211,0.00005843434,0.00003661241],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003954398,"about_ca_system_score_gemma":0.00004289169,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003714787,"about_ca_topic_score_gemma":0.00008082807,"domain_scores_codex":[0.9991297,0.00007151357,0.0001799195,0.0002369405,0.0001525368,0.0002293996],"domain_scores_gemma":[0.9992915,0.0001011724,0.0001062909,0.0002747066,0.0001523775,0.00007399447],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.005002446,0.00135967,0.7564001,0.0001239038,0.002287519,0.0002052,0.001114716,0.00008523078,0.126434,0.0002414009,0.02411775,0.08262803],"study_design_scores_gemma":[0.002051446,0.002548279,0.9811551,0.00001796091,0.0001007954,0.00005110058,0.000002841539,0.00003313131,0.003925973,0.0002232746,0.009806688,0.00008338239],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9839784,0.0001792107,0.0004690452,0.01382427,0.00005867846,0.0001553939,0.00001649236,0.00002329135,0.001295213],"genre_scores_gemma":[0.9917305,0.0002899623,0.00007493568,0.006540925,0.00003189288,0.000007052902,0.000006035687,0.00001940434,0.001299263],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.224755,"threshold_uncertainty_score":0.3701339,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03447953626562053,"score_gpt":0.2604154517572216,"score_spread":0.2259359154916011,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}