{"id":"W2566347645","doi":"10.1093/biolreprod/87.s1.496","title":"Benzo[a]pyrene Inhibition of Follicular Development and Survival Is Associated with Dysregulation of Hsp90, Bax, CYP1A1, and CYP1B1 Expression.","year":2012,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"Effects and risks of endocrine disrupting chemicals","field":"Environmental Science","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Follicular phase; Biology; Aryl hydrocarbon receptor; Ovarian follicle; Internal medicine; Follicle; Endocrinology; Andrology; Antral follicle; Ovulation; Benzo(a)pyrene; Oocyte; Embryo; Carcinogen; Hormone; Medicine; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001369717,0.0002034037,0.0001648179,0.0002680923,0.0002556096,0.000218549,0.0001128656,0.000147919,0.002016567],"category_scores_gemma":[0.0001331611,0.0001346513,0.0003475955,0.0002159982,0.0001982061,0.0001485011,0.0001572756,0.0003227201,0.0002721393],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002662237,"about_ca_system_score_gemma":0.0001984069,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00139977,"about_ca_topic_score_gemma":0.002345604,"domain_scores_codex":[0.9998745,0.00002241552,0.000009031297,0.00002513946,0.00003754778,0.00003136507],"domain_scores_gemma":[0.9998121,0.00002316858,0.00008245927,0.00002000822,0.00003923397,0.00002306057],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002304568,0.00006403364,0.003180101,0.0001775116,0.00003958342,0.0001658005,0.00003984495,0.00005718864,0.9892741,0.0001156322,0.0002317265,0.006423953],"study_design_scores_gemma":[0.00002894399,0.001200997,0.1787771,0.00002681217,0.00008976189,0.001143954,0.0001372046,0.0004507371,0.8074046,0.0002413913,0.01048634,0.00001203669],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9697935,0.02138228,0.003425903,0.0003848214,0.00007263264,0.0000515412,0.001003106,0.0001354341,0.003750879],"genre_scores_gemma":[0.9889328,0.007046051,0.0005816317,0.0000710259,0.00001650609,0.00002703834,0.0004675543,0.000009836591,0.002847496],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002016567,"threshold_uncertainty_score":0.006746113,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01219880028108007,"score_gpt":0.2793414607020673,"score_spread":0.2671426604209872,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}