{"id":"W2566485683","doi":"10.1021/acs.est.6b04695","title":"Effects on Biotransformation, Oxidative Stress, and Endocrine Disruption in Rainbow Trout (<i>Oncorhynchus mykiss</i>) Exposed to Hydraulic Fracturing Flowback and Produced Water","year":2016,"lang":"en","type":"article","venue":"Environmental Science & Technology","topic":"Atmospheric and Environmental Gas Dynamics","field":"Environmental Science","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Oxidative stress; Chemistry; Rainbow trout; Aryl hydrocarbon receptor; Trout; Lipid peroxidation; TBARS; Environmental chemistry; Nonylphenol; Reactive oxygen species; Biochemistry; Biology; Fishery","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002448776,0.0003018965,0.0002262565,0.0001190421,0.0002753996,0.00003019612,0.0003305912,0.0001122538,0.0001667711],"category_scores_gemma":[0.00003013755,0.0001993756,0.0000235466,0.0003679919,0.001720916,0.0006705612,0.0005449366,0.0001749077,0.0002026976],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007411031,"about_ca_system_score_gemma":0.000004292511,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003628433,"about_ca_topic_score_gemma":0.00002345009,"domain_scores_codex":[0.9977136,0.00003815045,0.0002785729,0.0008798304,0.000400975,0.0006888176],"domain_scores_gemma":[0.9993955,0.0000388711,0.0000604081,0.0003049441,9.764281e-7,0.0001992447],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003818034,0.0001000402,0.08905777,0.00000528831,0.000002834252,0.00001215333,0.0005980433,0.0006528106,0.8252839,0.00001641529,0.000003100033,0.08422939],"study_design_scores_gemma":[0.0007902151,0.0003916002,0.2271102,0.00004109744,0.000006656245,0.0000215096,0.0002868765,0.0002505885,0.7698243,0.0003577044,0.0006314698,0.0002877856],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949699,0.00002657073,0.001392768,0.002573341,0.00004010231,0.0007346985,0.000005341465,0.00006728626,0.0001899859],"genre_scores_gemma":[0.9973248,0.0001813614,0.001901199,0.0003208532,0.00001604696,0.00009062782,0.000002973678,0.00002011837,0.000142007],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1380525,"threshold_uncertainty_score":0.8130299,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002783301630876384,"score_gpt":0.1912391413357525,"score_spread":0.1884558397048761,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}