{"id":"W2566658724","doi":"10.1016/s1525-0016(16)34022-9","title":"413. Pre-Clinical Preparation and Validation of Tumor Cell-Based IL-12 Immunotherapy for Acute Myeloid Leukemia","year":2015,"lang":"en","type":"article","venue":"Molecular Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; Ontario Institute for Cancer Research","funders":"","keywords":"Tumor microenvironment; Cancer research; Immunotherapy; Biology; T cell; Myeloid leukemia; Leukemia; Immunology; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001542269,0.0004817192,0.0004111537,0.0003306255,0.0003818701,0.0006159046,0.0003372986,0.0005827462,0.003639047],"category_scores_gemma":[0.0005432125,0.0001720432,0.0003134024,0.0002490335,0.0003939966,0.000184826,0.0002393277,0.0007787143,0.002236977],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004260671,"about_ca_system_score_gemma":0.001024804,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008782716,"about_ca_topic_score_gemma":0.0008305423,"domain_scores_codex":[0.999283,0.0002171108,0.00004362126,0.00006601355,0.0002603636,0.0001298241],"domain_scores_gemma":[0.9996902,0.00003351289,0.00003291262,0.00005592622,0.0001084774,0.00007909503],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001176585,0.001573662,0.001147366,0.0001385383,0.00001682353,0.0001322213,0.00009518638,0.001013891,0.9727571,0.000369627,0.001110101,0.02046893],"study_design_scores_gemma":[0.0006464896,0.01744211,0.004186807,0.00004443883,0.00004928415,0.0003793343,0.00004984636,0.001794674,0.9483314,0.0001217974,0.02694129,0.00001245452],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9502214,0.001831822,0.02671411,0.0005489113,0.0002416109,0.006876363,0.002666905,0.0004873484,0.01041155],"genre_scores_gemma":[0.9576014,0.001584447,0.0230939,0.0003394831,0.00007424728,0.002207039,0.006106571,0.000115709,0.008877292],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003639047,"threshold_uncertainty_score":0.01217383,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03056492420356324,"score_gpt":0.3580838026826536,"score_spread":0.3275188784790903,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}