{"id":"W2566878474","doi":"10.1158/2326-6074.tumimm14-ia22","title":"Abstract IA22: Regulation of metabolic plasticity in effector T cells","year":2015,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Effector; Cell biology; Biology; AMPK; T cell; Acquired immune system; Bioenergetics; Immune system; Kinase; Protein kinase A; Immunology; Mitochondrion","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001287672,0.0003521013,0.0002670944,0.0002911601,0.0001887535,0.0006763061,0.0003751434,0.000367302,0.004424814],"category_scores_gemma":[0.0001206517,0.0001116586,0.0002032232,0.000258288,0.0002713468,0.0002478311,0.0002907892,0.0005834792,0.001286999],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004737597,"about_ca_system_score_gemma":0.0001919983,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002719603,"about_ca_topic_score_gemma":0.0003289478,"domain_scores_codex":[0.9998845,0.00001771078,0.000009361221,0.0000307886,0.00002876068,0.00002881809],"domain_scores_gemma":[0.9999241,0.000009585533,0.00002064491,0.000009612886,0.00001349107,0.00002259775],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002972798,0.00002826843,0.0002409085,0.00007564358,0.000004309012,0.0001441736,0.000009031582,0.0001716698,0.9916914,0.0005723368,0.0006233256,0.006141733],"study_design_scores_gemma":[0.0000486783,0.0003484885,0.01054719,0.00002220212,0.00001997169,0.0006093748,0.00004909369,0.001042105,0.9669619,0.0007861088,0.01954462,0.00002035369],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9104953,0.02377177,0.01725087,0.002845198,0.001080227,0.000132068,0.002243082,0.0008950189,0.04128655],"genre_scores_gemma":[0.9682433,0.005282213,0.003749847,0.0005001358,0.0001362527,0.00006548524,0.00121773,0.0001076399,0.02069741],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004424814,"threshold_uncertainty_score":0.01480246,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09428215381281056,"score_gpt":0.4004362073598178,"score_spread":0.3061540535470073,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}